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Jamie Winn NowPatientGreen tick
Updated on 26 Apr 2024

REXULTI Uses, Side Effects, Interactions, Warnings & Dosing

What is REXULTI?

What is REXULTI?

REXULTI is the brand name for brexipaprizole. It is an antipsychotic medication and available in tablet form.

What dosages is REXULTI available in?

What dosages is REXULTI available in?

REXULTI is available as a 0.25 mg, 0.5 mg, 1 mg, 2 mg, 3 mg, and 4 mg tablet formulation.

What is REXULTI used for?

What is REXULTI used for?

REXULTI is an antipsychotic that helps treat mental health conditions including major depressive disorder (MDD) in adults, schizophrenia in adults and pediatric patients ages 13 years and older; and agitation associated with dementia due to Alzheimer’s disease

How does REXULTI work?

How does REXULTI work?

REXULTI works by balancing chemicals in your brain, such as dopamine and serotonin. This helps to improve your thoughts, mood, and behaviors.

How do I take REXULTI?

How do I take REXULTI?

REXULTI is taken once a day with or without food. The typical daily dose is 0.5 mg to 4 mg.

Is it safe for me to take REXULTI?

Is it safe for me to take REXULTI?

REXULTI is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you.

REXULTI Common Side Effects

REXULTI Common Side Effects

Common side effects of REXULTI include: Fidgeting

  • Weight gain
  • Headache
  • Sleepiness
  • Tremor
  • Common cold
  • Larger appetite
  • Fatigue
  • Dizziness
  • Restlessness
  • Anxiety
  • Heartburn
  • Diarrhea
  • Constipation
REXULTI Serious Side Effects

REXULTI Serious Side Effects

Serious side effects are rare with REXULTI however they can include: Neuroleptic malignant syndrome (NMS), which can lead to death.
Impulse control problems: intense urges for and behaviors including gambling, shopping, binge eating, engaging in sexual activity
Extremely high blood sugar levels: feeling very hungry or thirsty, urinating more often, stomach pain, weakness, fruity-smelling breath
Uncontrolled muscle movements (tardive dyskinesia): involuntarily sticking out your tongue, puffing out your cheeks, puckering your mouth, lip smacking, chewing, and foot tapping Suicidal thoughts or behavior Seizures

Effects of other drugs, drug classes and over-the-counter products on REXULTI

Effects of other drugs, drug classes and over-the-counter products on REXULTI

The following medications may increase the levels and effects of REXULTI:

  • clarithromycin (BIAXIN)
  • fluoxetine (PROXAC)
  • paroxetine (PAXIL)
  • nefazodone
  • fluconazole (DIFLUCAN)
  • ketoconazole (NIZORAL)
  • itraconazole (SPORONOX)
  • Quinidine
  • indinavir (CRIXIVAN),
  • ritonavir (NORVIR)
  • saquinavir (FORTOVASE, INVIRASE)
  • lopinavir/ritonavir (KALETRA)
Who makes REXULTI?

Who makes REXULTI?


Is REXULTI safe in pregnancy?

Is REXULTI safe in pregnancy?

The use of REXULTI may cause extrapyramidal and/or withdrawal symptoms inneonates with third trimester exposure.


What to do if you missed your REXULTI dose

The FDA's medical product safety reporting program for health professionals, patients and consumers.

Learn more about reporting side effects
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Medical Disclaimer

NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.

The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.

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