Key facts about Brexpiprazole
What dosages is Brexpiprazole available in?
Brexpiprazole is available as a 0.25 mg, 0.5 mg, 1 mg, 2 mg, 3 mg, and 4 mg tablet formulation.
What is Brexpiprazole used for?
Brexpiprazole is an antipsychotic that helps treat mental health conditions including major depressive disorder (MDD) in adults, schizophrenia in adults and pediatric patients ages 13 years and older; and agitation associated with dementia due to Alzheimer’s disease
How does Brexpiprazole work?
Brexpiprazole works by balancing chemicals in your brain, such as dopamine and serotonin. This helps to improve your thoughts, mood, and behaviors.
How do I take Brexpiprazole?
Brexpiprazole is taken once a day with or without food. The typical daily dose is 0.5 mg to 4 mg.
Is it safe for me to take Brexpiprazole?
Brexpiprazole is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you.
Brexpiprazole Common Side Effects
Common side effects of Brexpiprazole include: Fidgeting
- Weight gain
- Headache
- Sleepiness
- Tremor
- Common cold
- Larger appetite
- Fatigue
- Dizziness
- Restlessness
- Anxiety
- Heartburn
- Diarrhea
- Constipation
Brexpiprazole Serious Side Effects
Serious side effects are rare with Brexpiprazole however they can include: Neuroleptic malignant syndrome (NMS), which can lead to death.
Impulse control problems: intense urges for and behaviors including gambling, shopping, binge eating, engaging in sexual activity
Extremely high blood sugar levels: feeling very hungry or thirsty, urinating more often, stomach pain, weakness, fruity-smelling breath
Uncontrolled muscle movements (tardive dyskinesia): involuntarily sticking out your tongue, puffing out your cheeks, puckering your mouth, lip smacking, chewing, and foot tapping Suicidal thoughts or behavior Seizures
Effects of other drugs, drug classes and over-the-counter products on Brexpiprazole
The following medications may increase the levels and effects of Brexpiprazole:
- clarithromycin (BIAXIN)
- fluoxetine (PROXAC)
- paroxetine (PAXIL)
- nefazodone
- fluconazole (DIFLUCAN)
- ketoconazole (NIZORAL)
- itraconazole (SPORONOX)
- Quinidine
- indinavir (CRIXIVAN),
- ritonavir (NORVIR)
- saquinavir (FORTOVASE, INVIRASE)
- lopinavir/ritonavir (KALETRA)
Who makes Brexpiprazole?
Various FDA-approved generic manufacturers
Is Brexpiprazole safe in pregnancy?
The use of Brexpiprazole may cause extrapyramidal and/or withdrawal symptoms inneonates with third trimester exposure.













