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MEDICAL INFORMATION
Resmetirom Key Facts
What dosages is Resmetirom available in?
Resmetirom is available as a 60 mg, 80 mg, and 100 mg oral tablet.
What is Resmetirom used for?
Resmetirom is a thyroid hormone receptor-beta (THR-beta) agonist indicated in conjunction with diet and exercise for the treatment of adults with noncirrhotic nonalcoholic steatohepatitis (NASH) with moderate to advanced liver fibrosis (consistent with stages F2 to F3 fibrosis).
How does Resmetirom work?
Resmetirom works by helping your body break down fat in the liver. This decreases inflammation and scarring.
How do I take Resmetirom?
Resmetirom dosing is is based on actual body weight. Your dose may be decreased if you are taking a CYP2C8 inhibitor.
Is it safe for me to take Resmetirom?
Resmetirom is a safe and effective treatment when used for FDA approved indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you.
Resmetirom Common Side Effects
Common side effects of Resmetirom: Diarrhea Itching Nausea Vomiting
Resmetirom Serious Side Effects
Serious side effects are rare with Resmetirom. Contact your healthcare provider immediately if you experience any of the following: Allergic reactions: skin rash, itching, hives, swelling of the face, lips, tongue, or throat Gallbladder problems: severe stomach pain, nausea, vomiting, fever Liver injury: right upper belly pain, loss of appetite, nausea, light-colored stool, dark yellow or brown urine, yellowing skin or eyes, unusual weakness or fatigue.
Effects of other drugs, drug classes and over-the-counter products on Resmetirom
The following medications may interact with Resmetirom: Strong or Moderate CYP2C8 Inhibitors: Concomitant use not recommended (strong inhibitor [e.g., gemfibrozil]); or reduce Resmetirom dosage (moderate inhibitor [e.g., clopidogrel]). OATP1B1 and OATP1B3 Inhibitors: Concomitant use with OATP inhibitors (e.g., cyclosporine) is not recommended. Atorvastatin, Pravastatin, Rosuvastatin and Simvastatin: Limit the daily dosage of the statin as recommended. â CYP2C8 Substrates: Monitor patients more frequently for substrate related adverse reactions.
Who makes Resmetirom?
Various FDA-approved generic manufacturers
Is Resmetirom safe in pregnancy?
It is not known whether Resmetirom will harm your unborn baby. Talk with your healthcare provider about the risks of taking this medication if you are pregnant or plan on becoming pregnant.
What is the brand name for Resmetirom?
Medical Disclaimer
NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.
The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.
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