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Rapamune Oral Solution is the brand name for sirolimus and is available as an oral solution.

Rapamune Oral Solution is available as a 1 mg/ml oral solution.

Rapamune Oral Solution is an immunosuppressant that is used to treat:
Prevention of kidney transplant rejection
Treatment of lymphangioleiomyomatosis (LAM)

Rapamune Oral Solution is an immunosuppressant that lowers the activity of your immune system. You need a suppressed (lowered) immune system after receiving a transplant so your body doesn’t reject the new kidney.

Rapamune Oral Solution is typically taken as 6 mg or 15 mg by mouth on the day after your transplant, followed by 2 mg or 5 mg by mouth every day. For lymphangioleiomyomatosis, the typical starting dose is 2 mg by mouth every day.
Your provider will likely measure the level of medication in your blood after a few weeks and will adjust your dose accordingly.

Rapamune Oral Solution is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you.

Serious side effects are rare with Rapamune Oral Solution. Contact your healthcare provider immediately if you experience any of the following.

Infection: fever, chills, fatigue, muscle aches
Serious lung problems (interstitial lung disease): breathing problems, chest pain, cough, tiredness
Serious allergic reaction: trouble breathing, swelling of the face, tightening of the throat, rash, hives, welts, peeling or blistering skin

The following medications may interact with Rapamune Oral Solution:

Pfizer

Rapamune Oral Solution should be used during pregnancy only if the potential benefit outweighs the potential risk to the
embryo/fetus.

• Sirolimus