View sirolimus savings options available to you including Manufacturer Coupons, Rx Advantage Savings Card, Canadian Prescription Savings or sirolimus Patient Assistance Program.

Programs are suitable for individuals who want to buy sirolimus without insurance, with insurance or for those who are underinsured. You can pay as little as $0 per fill.*

Manufactured by various FDA-approved generic manufacturers.

*Applicable to Drug Coupons & Patient Assistance Programs

This content is intended for US audiences only

Drug savings programs

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    Rx Advantage Card

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    Save up to 90%

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    Canadian Prescription Savings

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    Drug Coupons

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    Patient Assistance Programs

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Updated on 24 Apr 2024

Learn more about sirolimus

What dosages is sirolimus available in?

What dosages is sirolimus available in?

sirolimus is available as a 0.5 mg, 1 mg, and 2 mg oral tablet and a 1 mg/ml oral solution.

What is sirolimus used for?

What is sirolimus used for?

sirolimus is an immunosuppressant that is used to treat:
Prevention of kidney transplant rejection Treatment of lymphangioleiomyomatosis (LAM)

How does sirolimus work?

How does sirolimus work?

sirolimus is an immunosuppressant that lowers the activity of your immune system. You need a suppressed (lowered) immune system after receiving a transplant so your body doesn’t reject the new kidney.

How do I take sirolimus?

How do I take sirolimus?

sirolimus is typically taken as 6 mg or 15 mg by mouth on the day after your transplant, followed by 2 mg or 5 mg by mouth every day. For lymphangioleiomyomatosis, the typical starting dose is 2 mg by mouth every day. Your provider will likely measure the level of medication in your blood after a few weeks and will adjust your dose accordingly.

Is it safe for me to take sirolimus?

Is it safe for me to take sirolimus?

sirolimus is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you.

sirolimus Common Side Effects

sirolimus Common Side Effects

Common side effects of sirolimus:

  • Swelling in arms and legs
  • More cholesterol and fat in the blood
  • High blood pressure
  • Change in kidney labs
  • Constipation
  • Headache
  • Pain
  • Stomach pain
  • Urinary tract infection
sirolimus Serious Side Effects

sirolimus Serious Side Effects

Serious side effects are rare with sirolimus. Contact your healthcare provider immediately if you experience any of the following.

  • Infection: fever, chills, fatigue, muscle aches
  • Serious lung problems (interstitial lung disease): breathing problems, chest pain, cough, tiredness
  • Serious allergic reaction: trouble breathing, swelling of the face, tightening of the throat, rash, hives, welts, peeling or blistering skin
Effects of other drugs, drug classes and over-the-counter products on sirolimus

Effects of other drugs, drug classes and over-the-counter products on sirolimus

The following medications may interact with sirolimus:

  • Avoid concomitant use with strong CYP3A4/P-gp inducers or strong CYP3A4/P-gp inhibitors that decrease or increase sirolimus
  • concentrations
  • See full prescribing information for complete list of clinically significant drug interactions
Who makes sirolimus?

Who makes sirolimus?

Various FDA-approved generic manufacturers

Is sirolimus safe in pregnancy?

Is sirolimus safe in pregnancy?

sirolimus should be used during pregnancy only if the potential benefit outweighs the potential risk to the


What to do if you missed your sirolimus dose

The FDA's medical product safety reporting program for health professionals, patients and consumers.

Learn more about reporting side effects
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Drug Savings Tips

Medical Disclaimer

NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.

The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.

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