RAPAMUNE
Used for Immunosuppressant
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Manufactured by Pfizer
*You can pay as little as $0 per fill using Drug Coupons or Patient Assistance Programs. Subject to applicability & eligibility requirements.
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RAPAMUNE Uses, Side Effects, Interactions, Warnings & Dosing
What is RAPAMUNE?
RAPAMUNE is the brand name for sirolimus and is available as an oral tablet and solution.
What dosages is RAPAMUNE available in?
RAPAMUNE is available as a 0.5 mg, 1 mg, and 2 mg oral tablet and a 1 mg/ml oral solution.
What is RAPAMUNE used for?
RAPAMUNE is an immunosuppressant that is used to treat:
Prevention of kidney transplant rejection Treatment of lymphangioleiomyomatosis (LAM)
How does RAPAMUNE work?
RAPAMUNE is an immunosuppressant that lowers the activity of your immune system. You need a suppressed (lowered) immune system after receiving a transplant so your body doesn’t reject the new kidney.
How do I take RAPAMUNE?
RAPAMUNE is typically taken as 6 mg or 15 mg by mouth on the day after your transplant, followed by 2 mg or 5 mg by mouth every day. For lymphangioleiomyomatosis, the typical starting dose is 2 mg by mouth every day. Your provider will likely measure the level of medication in your blood after a few weeks and will adjust your dose accordingly.
Is it safe for me to take RAPAMUNE?
RAPAMUNE is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you.
RAPAMUNE Common Side Effects
Common side effects of RAPAMUNE:
- Swelling in arms and legs
- More cholesterol and fat in the blood
- High blood pressure
- Change in kidney labs
- Constipation
- Headache
- Pain
- Stomach pain
- Urinary tract infection
RAPAMUNE Serious Side Effects
Serious side effects are rare with RAPAMUNE. Contact your healthcare provider immediately if you experience any of the following.
- Infection: fever, chills, fatigue, muscle aches
- Serious lung problems (interstitial lung disease): breathing problems, chest pain, cough, tiredness
- Serious allergic reaction: trouble breathing, swelling of the face, tightening of the throat, rash, hives, welts, peeling or blistering skin
Effects of other drugs, drug classes and over-the-counter products on RAPAMUNE
The following medications may interact with RAPAMUNE:
- Avoid concomitant use with strong CYP3A4/P-gp inducers or strong CYP3A4/P-gp inhibitors that decrease or increase sirolimus
- concentrations
- See full prescribing information for complete list of clinically significant drug interactions
Who makes RAPAMUNE?
Pfizer
Is RAPAMUNE safe in pregnancy?
RAPAMUNE should be used during pregnancy only if the potential benefit outweighs the potential risk to the
embryo/fetus.
The FDA's medical product safety reporting program for health professionals, patients and consumers.
Learn more about reporting side effects
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Medical Disclaimer
NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.
The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.
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