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MEDICAL INFORMATION
Raltegravir Key Facts
What dosages is Raltegravir available in?
Raltegravir is available as a 400 mg oral tablet, a 25 mg and 100 mg chewable tablet, and a 100 mg oral suspension.
What is Raltegravir used for?
Raltegravir is a HIV ARV and is used for the following:
- HIV treatment
- HIV post-exposure prophylaxis (PEP)
How does Raltegravir work?
Raltegravir is an integrase inhibitor. Integrase is an enzyme that the HIV virus uses to enter your cells and make more copies of itself. When integrase is stopped, the virus cannot grow and spread.
How do I take Raltegravir?
Raltegravir is typically dosed as follows:
- Adults: The typical dose is 1 tablet (400 mg) twice daily OR for the HD tablet, 2 tablets (1200 mg) once daily
- Children: The dose is based on the child’s weight
Is it safe for me to take Raltegravir?
Raltegravir is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you.
Raltegravir Common Side Effects
Common side effects of Raltegravir:
- Headache
- Trouble sleeping
- Nausea
Raltegravir Serious Side Effects
Serious side effects are rare with Raltegravir. Contact your healthcare provider immediately if you experience any of the following.
- Muscle pain/damage (rhabdomyolysis)
- Allergic or severe skin reaction (severe rash, face swelling difficulty breathing)
Effects of other drugs, drug classes and over-the-counter products on Raltegravir
The following medications may interact with Raltegravir:
- Coadministration of Raltegravir or Raltegravir HD and other drugs may alter the plasma concentration of Raltegravir. The potential for drug-drug interactions must be considered prior to and during therapy
- Coadministration of Raltegravir or Raltegravir HD with drugs that are strong inducers of UGT1A1, such as rifampin, may result in reduced plasma concentrations of Raltegravir
Who makes Raltegravir?
Various FDA-approved generic manufacturers
Is Raltegravir safe in pregnancy?
It is not known if Raltegravir can harm your unborn baby. Raltegravir should only be used during pregnancy if the benefit to you is worth the possible risk to your baby.
There is a pregnancy exposure registry that monitors pregnancy outcomes in women. Healthcare providers are encouraged to register patients by calling the Antiretroviral Pregnancy Registry (APR) at 1- 800-258-4263.
What is the brand name for Raltegravir?
Medical Disclaimer
NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.
The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.
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We are a broad skilled and passionate group of clinicians with experience of operating in health systems in the United Kingdom & United States. Providing excellent care and advice is at the heart of everything we do. You can read more about our medical team by visiting the medical team page or learn more about how we curate content by visiting our editorial process
Monica Khosla
Medical Writer
Amish Patel
Pharmacist Independent Prescriber, Superintendant Pharmacist, Pharmacist
Navin Khosla
UK Responsible Person (UKRP), Pharmacist Independent Prescriber, Clinical Safety Officer (CSO), Pharmacist
Ketan Patel
Pharmacist Independent Prescriber, Pharmacist
Daniel Cheung
Pharmacist Independent Prescriber, Pharmacist
Jamie Winn
US Board Certified Pharmacist
Stefano Mirabello
Pharmacist Independent Prescriber, Clinical Safety Officer (CSO), Pharmacist
DeLon Canterbury
US Board Certified Pharmacist/PGX & Deprescribing Specialist
Rajive Patel
Medical Writer
Ihtesham Sabri
Medical Director
Aseel Hamoud Bedan
Hospital Consultant