Key facts about Pristiq
What is Pristiq?
Pristiq is the brand name for desvenlafaxine and is available as an extended-release oral tablet.
What dosages is Pristiq available in?
Pristiq is available as a 50 mg and 100 mg extended-release oral tablet.
What is Pristiq used for?
Pristiq is a SNRI that is used to treat depression.
How does Pristiq work?
Pristiq is a serotonin and norepinephrine reuptake inhibitor (SNRI). It raises serotonin and norepinephrine activity in the brain. These two natural chemicals help regulate your mood.
How do I take Pristiq?
Pristiq is typically taken as 50 mg by mouth once a day with or without food. Your dose might differ if you have kidney problems.
Is it safe for me to take Pristiq?
Pristiq is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. You should not use this medication if you have a known hypersensitivity to desvenlafaxine succinate, venlafaxine hydrochloride or any excipients in the Pristiq formulation or have taken an MAOI in the past 14 days.
Pristiq Common Side Effects
Common side effects of Pristiq:
- Nausea
- Dizziness
- Dry mouth
- Excessive sweating
- Constipation
- Trouble sleeping
- Feeling tired
- Loss of appetite
- Sleepiness
- Low sex drive
Pristiq Serious Side Effects
Serious side effects are rare with Pristiq. Contact your healthcare provider immediately if you experience any of the following.
- Suicidal thoughts or behavior
- Serotonin syndrome: fast heart rate, sweating, muscle stiffness, fever, confusion
- High blood pressure: severe headache, confusion, chest pain, blurred vision
- Unusual bleeding or bruising
- Seizures
- Low sodium levels in the blood: headache, difficulty concentrating, confusion, memory problems, weakness
Effects of other drugs, drug classes and over-the-counter products on Pristiq
The following medications may interact with Pristiq:
- Other serotonergic drugs – Increases the risk of serotonin syndrome
- Antiplatelet or anticoagulant drugs – May increase the risk of bleeding
- CYP3A inhibitors – May increase the risk of toxicity of Pristiq
Who makes Pristiq?
Pfizer Inc.
Is Pristiq safe in pregnancy?
There are no adequate and well-controlled studies of Pristiq in pregnant women. Therefore, Pristiq should be used during pregnancy only if the potential benefits justify the potential
risks.













