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Pravachol is the brand name for pravastatin and is available as an oral tablet.

Pravachol is available as a 10 mg, 20 mg, 40 mg, and 80 mg oral tablet.

Pravachol is a statin that is used to:

• Lower the risk of heart or blood vessel problems (e.g., heart attack, stroke) in adults at risk for heart problems
• Lower “bad” cholesterol and triglyceride levels in certain adults
• Lower “bad” cholesterol levels in children age 8 years and older with heterozygous familial hypercholesterolemia (HeFH)

Pravachol is a statin. It works by blocking a protein in your liver that makes cholesterol. This lowers the amount of “bad” cholesterol (called low-density lipoprotein, or LDL) in your blood. Pravachol might also help raise your “good” cholesterol (called high-density lipoprotein, or HDL) levels and lower your triglyceride levels. As a result, Pravachol helps lower the risk of coronary artery disease, heart attack, and stroke.

Pravachol is typically taken at dose ranges from 10 mg to 80 mg by mouth once per day. Your provider will change your dose depending on different factors, such as your cholesterol levels, kidney function, side effects that you’re having, or other medications you might be taking.

Pravachol is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. You should not use this medication for the following:

• Hypersensitivity to any component of this medication.
  Active liver disease or unexplained, persistent elevations of serum transaminases
• Women who are pregnant or may become pregnant.
  Nursing mothers

Common side effects of Pravachol:

• Muscle, joint, or bone pain
• Upper respiratory infection
• Chest pain
• Nausea or vomiting
• Tiredness
• Headache

Serious side effects are rare with Pravachol. Contact your healthcare provider immediately if you experience any of the following.

• Severe muscle damage (rhabdomyolysis): dark brown urine, severe muscle weakness or pain, fever, tiredness
• Liver problems: swelling of your stomach, yellowing of your skin or the whites of your eyes, confusion, dark or brown urine

The following medications may interact with Pravachol:

• Concomitant lipid-lowering therapies: use with fibrates or lipid-modifying doses (≥1 g/day) of niacin increases the risk of adverse skeletal muscle
• effects. Caution should be used when prescribing with Pravachol
• Cyclosporine: combination increases exposure. Limit pravastatin to 20 mg once daily
• Clarithromycin: combination increases exposure. Limit pravastatin to 40 mg once daily

Bristol-Myers Squibb

Pravachol may cause harm to your unborn baby. Discontinue Pravachol when pregnancy is recognized.

• Pravastatin