Save on Ponesimod with Coupons, Discounts & Savings Programs

Ponesimod is available as a 2 mg, 3 mg, 4 mg, 5 mg, 6 mg, 7 mg, 8 mg, 9 mg, 10 mg, and 20 mg oral tablet.

• Ponesimod is a sphingosine 1-phosphate receptor modulator that is used for the treatment of mutiple sclerosis (MS) relapses, including clinically isolated syndrome, relapsing-remiting disease, and active secondary progressive disease.

Ponesimod is a sphingosine 1-phosphate receptor modulator. It’s not known exactly how Ponesimod works for multiple sclerosis, but it might be due to how this medication lowers the number of lymphocytes (white blood cells) from entering your nervous system and preventing it from causing swelling and damage to your body.

• If you’re starting Ponesimod for the first time, your provider will typically prescribe the Ponesimod starter pack. You’ll start with 2 mg by mouth once daily and follow the dose titration schedule for 2 weeks to reach 10 mg daily.
• Maintenance dose:
• After completing the starter pack, the typical maintenance dose for Ponesimod is 20 mg by mouth once daily.

Ponesimod is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. You should not use this medication if any of these apply:
In the last 6 months, experienced myocardial infarction, unstable angina,
stroke, transient ischemic attack (TIA), decompensated heart failure requiring hospitalization, or Class III/IV heart failure.
Presence of Mobitz type II second-degree, third-degree AV block, sick sinus syndrome, or sino-atrial block, unless the patient has a functioning
pacemaker.

• Common side effects of Ponesimod:
• Upper respiratory infection
• Abnormal liver tests
• High blood pressure
• Urinary tract infection
• Difficulty breathing
• Dizziness
• Cough
• Arm and leg pain
• Sleepiness
• Fever
• Rise in C-reactive protein levels (measures inflammation)
• High cholesterol
• Off balance or lightheadedness

Serious side effects are rare with Ponesimod. Contact your healthcare provider immediately if you experience any of the following.

Infections: fever, tiredness, body aches, chills, nausea, vomiting, headache with fever, neck stiffness, sensitivity to light, or confusion
Slow heart rate: dizziness, lightheadedness, shortness of breath, confusion, chest pain, tiredness, or feeling like your heart is beating slowly or skipping a beat
Breathing problems: shortness of breath
Liver problems: unexplained nausea, vomiting, stomach pain, tiredness, anorexia (eating disorder), yellowing of skin or eyes, or dark urine
Vision changes: blurry vision, blind spot in center of vision, sensitivity to light, unusually colored vision

• The following medications may interact with Ponesimod:
• Vaccines: Avoid live attenuated vaccines during and for up to 1-2 weeks
• after treatment with Ponesimod.
• • Strong CYP3A4 and UGT1A1 Inducers: Coadministration with
• Ponesimod is not recommended.

Various FDA-approved generic manufacturers

Based on animal studies, Ponesimod may cause fetal harm. Because it takes approximately 1 week to eliminate Ponesimod from the body, women of childbearing potential should use effective contraception to avoid pregnancy during and for 1 week after stopping Ponesimod treatment.

• Ponvory