PONVORY
NowPatient helps you obtain your PONVORY prescription for free or at low-cost. Drug savings programs are suitable for individuals who are insured, don't have insurance or are underinsured and can't afford your medicine.
Manufactured by Janssen Pharmaceuticals
*You can pay as little as $0 per fill using Drug Coupons or Patient Assistance Programs. Subject to applicability & eligibility requirements.
This content is intended for US audiences only
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PONVORY key facts
What is PONVORY?
PONVORY is the brand name for ponesimod and is available as an oral tablet.
What dosages is PONVORY available in?
PONVORY is available as a 2 mg, 3 mg, 4 mg, 5 mg, 6 mg, 7 mg, 8 mg, 9 mg, 10 mg, and 20 mg oral tablet.
What is PONVORY used for?
- PONVORY is a sphingosine 1-phosphate receptor modulator that is used for the treatment of mutiple sclerosis (MS) relapses, including clinically isolated syndrome, relapsing-remiting disease, and active secondary progressive disease.
How does PONVORY work?
PONVORY is a sphingosine 1-phosphate receptor modulator. It’s not known exactly how PONVORY works for multiple sclerosis, but it might be due to how this medication lowers the number of lymphocytes (white blood cells) from entering your nervous system and preventing it from causing swelling and damage to your body.
How do I take PONVORY?
- If you’re starting PONVORY for the first time, your provider will typically prescribe the PONVORY starter pack. You’ll start with 2 mg by mouth once daily and follow the dose titration schedule for 2 weeks to reach 10 mg daily.
- Maintenance dose:
- After completing the starter pack, the typical maintenance dose for PONVORY is 20 mg by mouth once daily.
Is it safe for me to take PONVORY?
PONVORY is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. You should not use this medication if any of these apply:
In the last 6 months, experienced myocardial infarction, unstable angina,
stroke, transient ischemic attack (TIA), decompensated heart failure requiring hospitalization, or Class III/IV heart failure.
Presence of Mobitz type II second-degree, third-degree AV block, sick sinus syndrome, or sino-atrial block, unless the patient has a functioning
pacemaker.
PONVORY Common Side Effects
- Common side effects of PONVORY:
- Upper respiratory infection
- Abnormal liver tests
- High blood pressure
- Urinary tract infection
- Difficulty breathing
- Dizziness
- Cough
- Arm and leg pain
- Sleepiness
- Fever
- Rise in C-reactive protein levels (measures inflammation)
- High cholesterol
- Off balance or lightheadedness
PONVORY Serious Side Effects
Serious side effects are rare with PONVORY. Contact your healthcare provider immediately if you experience any of the following.
Infections: fever, tiredness, body aches, chills, nausea, vomiting, headache with fever, neck stiffness, sensitivity to light, or confusion
Slow heart rate: dizziness, lightheadedness, shortness of breath, confusion, chest pain, tiredness, or feeling like your heart is beating slowly or skipping a beat
Breathing problems: shortness of breath
Liver problems: unexplained nausea, vomiting, stomach pain, tiredness, anorexia (eating disorder), yellowing of skin or eyes, or dark urine
Vision changes: blurry vision, blind spot in center of vision, sensitivity to light, unusually colored vision
Effects of other drugs, drug classes and over-the-counter products on PONVORY
- The following medications may interact with PONVORY:
- Vaccines: Avoid live attenuated vaccines during and for up to 1-2 weeks
- after treatment with PONVORY.
- • Strong CYP3A4 and UGT1A1 Inducers: Coadministration with
- PONVORY is not recommended.
Who makes PONVORY?
Janssen Pharmaceuticals
Is PONVORY safe in pregnancy?
Based on animal studies, PONVORY may cause fetal harm. Because it takes approximately 1 week to eliminate PONVORY from the body, women of childbearing potential should use effective contraception to avoid pregnancy during and for 1 week after stopping PONVORY treatment.
The FDA's medical product safety reporting program for health professionals, patients and consumers.
Learn more about reporting side effects in the USDrug Savings Guide
A practical guide to saving money and receiving support with prescription costs
How can NowPatient help me to lower the cost of my PONVORY prescription?
After you create a FREE account with NowPatient, you will have access to 4 programs that can help lower the cost of your PONVORY prescription
Applicability to each program will be dependent on your insurance status.
How do the NowPatient PONVORY savings programs work?
After you have created your FREE account with NowPatient, you can access the various programs from your account dashboard. Each program has clear instructions on how to check your eligibility. You can see how the process works by clicking on the feature link below and seeing the ‘How it works’ steps.
Drug Coupon and Patient Assistance Programs require an eligibility quiz to be completed.
Are the NowPatient PONVORY savings programs suitable for everyone, regardless of insurance status?
No. Each program has its own eligibility and applicability requirements. The table below shows if a program is available to you, based on your insurance status.
| Rx Advantage Card* for PONVORY | Canadian Prescription Savings* for PONVORY | PONVORY Drug Coupon* | PONVORY Patient Assistance Program* | |
| Insured (federal, state or government) | Available | Available | Not Available | Available If Offered by Pharmaceutical Company |
| Insured (Commercial or Private) | Available | Available | Available If Offered by Pharmaceutical Company | Available If Offered by Pharmaceutical Company |
| Uninsured | Available | Available | Not Available | Available If Offered by Pharmaceutical Company |
| Insured but without pharmacy benefit or drug coverage | Available | Available | Not Available | Available If Offered by Pharmaceutical Company |
*This is not insurance.
Are the NowPatient drug savings programs suitable for brand and generic versions of PONVORY?
No. Each program has applicability requirements. Please see below
| Rx Advantage Card* for PONVORY | Canadian Prescription Savings* for PONVORY | PONVORY Drug Coupon* | PONVORY Patient Assistance Program* | |
| Brand | Yes | Yes | Yes, If Offered by Pharmaceutical Company | Yes, If Offered by Pharmaceutical Company |
| Generic | Yes | Yes | No | No |
*This is not insurance.
If you have Medicare Part D or Medicare Advantage and none of the PONVORY savings options are applicable or affordable for me, what can you do?
If you are insured with Medicare and the PONVORY drug savings options are not applicable to you and still remain unaffordable, then you can check Medicaid eligibility in your state by following the instructions at HealthCare.gov.
The government site is easy to use and after you have selected your state, it will navigate you to the appropriate contact point to make the application. State Medicaid programs may cover the full cost of your medication.
People who qualify for both Medicare and Medicaid are called ‘dual eligibles’.
If you are denied Medicaid for PONVORY, and you are still unable to afford your copay or co-insurance element (for example if you are in the coverage gap or Donut Hole) then you may be eligible for a federal support program like Low Income Subsidy. To be eligible for Low Income Subsidy, you need to be a resident in one of the 50 States or the District of Columbia. You can check eligibility online at SSA Medicare D Extra Help. You can also call Social Security at 1-800-772-1213 (TTY 1-800-325-0778).
I am uninsured or underinsured and none of the PONVORY prescription saving options are applicable or affordable for me, what can I do?
If you are uninsured or underinsured (for example, PONVORY is not covered by your plan) and the drug savings options are not applicable or still unaffordable, then you can check Medicaid eligibility in your state by following the instructions at HealthCare.gov.
The government site is easy to use and you can select your state and it will navigate you to the appropriate contact point to make the application. State Medicaid programs may cover the full cost of your medication.
If you are denied and all else fails, and if you have been prescribed PONVORY for an FDA-approved indication, you can call the pharmaceutical company to see if they have any other assistance programs.
I am commercially or privately insured and none of the PONVORY prescription saving options are applicable or affordable for me, what can I do?
If your medication is not covered by your plan, you can you can appeal your insurance company’s decision. Sometimes, a formal appeal can result in the drug being covered if it is deemed medically necessary.
If you cannot afford your copay, then you can check Medicaid eligibility in your state by following the instructions at HealthCare.gov.
However, being privately insured might complicate your eligibility for Medicaid, as having private insurance may be considered in the financial eligibility assessment.
The government site is easy to use and you can select your state and it will navigate you to the appropriate contact point to make the application. If you qualify, state Medicaid may cover the full cost of your medication.
If I have federal, state or commercial insurance and none of the PONVORY prescription saving options are applicable or affordable for me, are there any other support organisations that can help me with my co-insurance or copay?
If you have already tried Medicaid and received a denial letter or if you are insured with Medicare and have been denied Low-Income Subsidy, then you can try one of the following organizational support programs:
1. Patient Access Network Foundation (PAN) assistance for PONVORY
If you are having trouble paying for your PONVORY medication due to unaffordable copays or deductibles, the Patient Access Network Foundation (PAN), may be able to assist you. To qualify for PAN assistance for PONVORY you will need to meet one or all of the following criteria:
- Your income is below 400% of the federal poverty level
- PONVORY is prescribed for an approved FDA indication
- You live in and receive treatment in the United States or U.S. territories, even if you do not have U.S. citizenship
- You have Medicare insurance coverage that covers PONVORY
- If PONVORY is listed on PAN’s list of covered medications
You can check the Patient Access Network Foundation Website for more information.
2. HealthWell Foundation Copay Program for PONVORY
If you are having trouble paying for your PONVORY medication due to unaffordable copays or deductibles, the HealthWell Foundation Copay Program may be able to assist you. To qualify for assistance for PONVORY you will need to meet the following criteria:
- You live in and are being treated in the United States
- You are insured and your plan covers PONVORY
- If PONVORY is listed on the HealthWell Foundation’s list of covered medications
You can check the HealthWell Foundation Website for more information.
3. Patient Advocate Foundation Co-Pay Relief Program for PONVORY
Patient Advocate Foundation’s Co-Pay Relief program exists to help reduce the financial distress you or your family may face when paying for your PONVORY treatment. If you qualify and can demonstrate the need, the foundation will provide you with direct payment covering co-pays, co-insurance, and deductibles. To qualify for assistance for PONVORY you will need to meet the following criteria:
- You must be currently insured and have coverage for PONVORY
- You must have a confirmed diagnosis and treatment plan
- You must reside and receive treatment in the United States
- Your Income must fall at or below 300% or 400% of the Federal Poverty Guideline (FPG) with consideration for the Cost of Living Index (COLI) and number in the household
- Applications can also be completed by contacting the program sponsor, toll-free at 866-512-3861.
You can check the Patient Advocate Foundation Website for more information.
Medical Disclaimer
NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.
The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.
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