PIQRAY®

Coupons, Savings & Patient Assistance

Learn more about PIQRAY® and see what savings options may be available to you that can help bring down the cost of your medication.

Options may include Rx Advantage Card, Copay assistance & Coupons, or Patient Assistance Programs. Suitable for insured, underinsured or uninsured individuals. Pay as little as $0 per fill.

Manufactured by Novartis Pharmaceuticals.

This content is intended for US audiences only

Drug savings options

Qualified

Rx Advantage Card for PIQRAY®

Good News! You can save up to 90% savings on the cost of your PIQRAY® when using the FREE NowPatient’s Rx Advantage Card at your local pharmacy.

Coming Soon

Canada Pharmacy for PIQRAY®

Use our trusted Canada Pharmacy partner, Prescription Help, for your PIQRAY®. It’s suitable if you are cash paying, uninsured or insured and cannot afford your copays.

Options
Coming Soon
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Coming Soon
Available

Copay Assistance for PIQRAY®

Novartis Pharmaceuticals who manufactures PIQRAY®, offers a co-pay assistance program to help those who are commercially insured but cannot meet the costs of the existing co-payment or co-insurance.

If you qualify, we can supply you with details of how to enroll and start saving.

Available

Patient Assistance Programs for PIQRAY®

Novartis Pharmaceuticals who manufactures PIQRAY®, offers a patient assistance program for those who are unable to afford their medication or do not have adequate coverage.

If you qualify, we can supply you with all the details to help you get started with your enrollment.

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Jamie Winn NowPatientGreen tick
Written by Rajive Patel, BPharm
Updated on 4 Apr 2024
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Learn more about PIQRAY

What is PIQRAY?

What is PIQRAY?

PIQRAY is the brand name for alpelisib and is available as an oral tablet.

What dosages is PIQRAY available in?

What dosages is PIQRAY available in?

PIQRAY is available as a 50 mg, 150 mg, and 200 mg oral tablet.

What is PIQRAY used for?

What is PIQRAY used for?

PIQRAY is an anticancer agent and is used to treat metastatic or advanced breast cancer that’s hormone receptor (HR)-positive, human epidermal growth factor receptor 2 (HER2)-negative, with PIK3CA mutations (in females who’ve gone through menopause and in males).

How does PIQRAY work?

How does PIQRAY work?

PIQRAY is a kinase inhibitor. It targets proteins made by the PIK3CA gene. Typically, these proteins send signals to help cells grow and divide. In people with certain types of breast cancer, there are changes to their PIK3CA gene (mutations). These mutations cause the proteins made by the PIK3CA gene to send too many signals. This leads to the cancer cells growing and dividing very fast. PIQRAY blocks the PIK3CA proteins from sending too many signals to cancer cells. With less signals to grow, the cancer cells won’t be able to grow as fast.

How do I take PIQRAY?

How do I take PIQRAY?

PIQRAY is typically taken as 300 mg by mouth once daily.

Is it safe for me to take PIQRAY?

Is it safe for me to take PIQRAY?

PIQRAY is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you.

PIQRAY Common Side Effects

PIQRAY Common Side Effects

Common side effects of PIQRAY:

  • High blood sugar
  • Higher creatinine levels
  • Diarrhea
  • Low white blood cell count
  • Higher liver enzyme levels
  • Rash
  • Nausea
  • Tiredness
  • Low red blood cell count
  • Loss of appetite
  • Painful sores in the mouth and throat
  • Vomiting
  • Weight loss
  • Lower calcium, potassium, and magnesium levels
  • Longer activated partial thromboplastin time
  • Hair loss
PIQRAY Serious Side Effects

PIQRAY Serious Side Effects

Serious side effects are rare with PIQRAY. Contact your healthcare provider immediately if you experience any of the following.

Dangerously high blood sugar: dry mouth, feeling thirsty, confusion, headache, nausea or vomiting, fruity breath, dry or flushed skin, fast breathing, urinating more often, experiencing weight loss while feeling more hungry
Serious lung problems: trouble breathing, dry cough, feeling very tired or weak, not feeling hungry, chest pain and discomfort
Severe allergic reaction: hives, difficulty breathing, swelling of the lips, tongue, or face
Severe skin reactions: skin rash, blisters on skin, peeling skin, fever

Effects of other drugs, drug classes and over-the-counter products on PIQRAY

Effects of other drugs, drug classes and over-the-counter products on PIQRAY

The following medications may interact with PIQRAY:

  • CYP3A4 Inducers: Avoid coadministration of PIQRAY with a strong
  • CYP3A4 inducer. Consider an alternative concomitant drug with no or
  • minimal potential to induce CYP3A4.
  • Breast Cancer Resistance Protein (BCRP) Inhibitors: Avoid the use of
  • BCRP inhibitors in patients treated with PIQRAY. If unable to use
  • alternative drugs, closely monitor for increased adverse reactions.
Who makes PIQRAY?

Who makes PIQRAY?

Novartis Pharmaceuticals

Is PIQRAY safe in pregnancy?

Is PIQRAY safe in pregnancy?

PIQRAY can harm your unborn baby.
Females who are able to become pregnant:
Your healthcare provider will check to see if you are pregnant before you start treatment with PIQRAY.
You should use effective birth control (contraception) during treatment with PIQRAY and for 1 week after the last dose.
Talk to your healthcare provider about birth control methods that may be right for you during this time.
If you become pregnant or think you are pregnant, tell your healthcare provider right away.

Males with female partners who are able to become pregnant:
You should use condoms and effective birth control during treatment with PIQRAY and for 1 week after the last dose.
If your female partner becomes pregnant, tell your healthcare provider right away.

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What to do if you missed your PIQRAY ® dose

The FDA's medical product safety reporting program for health professionals, patients and consumers.

Learn more about reporting side effects

What can I do if I am commercially insured but cannot afford my PIQRAY ®?

If you are commercially insured and you cannot afford your PIQRAY® copay or co-insurance you have four options:

Option

Savings Information

Copay Assistance Program

Check at the top of the page to see if there is a PIQRAY® Copay Assistance Program sponsored by the manufacturer. You can check your eligibility to see if you qualify. If you qualify you could obtain your PIQRAY® for as little as $0 per fill.

Patient Assistance Program

Check at the top of the page to see if there is a PIQRAY® Patient Assistance Program sponsored by the manufacturer. You can check your eligibility to see if you qualify. If you qualify you could obtain your PIQRAY® for no cost.

Rx Advantage Card

You can use the NowPatient Rx Advantage Card which removes the constraints of insurance and the cost can be typically lower than your plan copay or co-insurance. If you elect to use this method, out of pocket costs do not contribute towards your plan deductibles.

Medicaid

If the above options are not feasible then you can check Medicaid eligibility in your state by following this link to the HealthCare.gov. The government site is easy to use and you can select your state and it will navigate you to the appropriate contact point to make the application. State Medicaid programs may cover the full cost of your medication.

What can I do if I am uninsured and cannot afford my PIQRAY ®?

If you are uninsured and you cannot afford your PIQRAY®, then you have three options:

Option

Savings Information

Patient Assistance Program

Check at the top of the page to see if there is a PIQRAY® Patient Assistance Program sponsored by the manufacturer. You can check your eligibility to see if you qualify. If you qualify you could obtain your PIQRAY® for no cost.

Rx Advantage Card

You can use the NowPatient Rx Advantage Card at a local pharmacy and obtain prices that are typically 80% of standard retail prices.

Medicaid

If the above options are not feasible then you can check Medicaid eligibility in your state by following this link to the HealthCare.gov. The government site is easy to use and you can select your state and it will navigate you to the appropriate contact point to make the application. State Medicaid programs may cover the full cost of your medication.

What can I do if I am insured with Medicare and cannot afford my PIQRAY ®?

If you are insured with Medicare and have Part D or an Advantage drug plan but cannot afford your copay or co-insurance element (for example if you are in the coverage gap or Donut Hole) then you have four options:

Option

Savings Information

Patient Assistance Program

Check at the top of the page to see if there is a PIQRAY® Patient Assistance Program sponsored by the manufacturer. You can check your eligibility to see if you qualify. If you qualify you could obtain your PIQRAY® for no cost.

Rx Advantage Card

You can use the NowPatient Rx Advantage Card which removes the constraints of insurance and the cost can be typically lower than your plan copay or co-insurance. If you elect to use this method, out of pocket costs do not contribute towards your plan deductibles.

Low Income Subsidy

If this is still too expensive or unaffordable then you can apply for federal support like Low Income Subsidy (LIS). To be eligible for Low Income Subsidy, you need to be resident in one of the 50 States or the District of Columbia. You can check eligibility online at SSA Medicare D Extra Help. You can also call Social Security at 1-800-772-1213 (TTY 1-800-325-0778).

Medicaid

The final option is to check ‘dual eligibility’ to Medicaid in your state by following this link to the HealthCare.gov. The government site is easy to use and you can select your state and it will navigate you to the appropriate contact point to make the application. State Medicaid programs may cover the full cost of your medication.

Am I eligible for the Rx Advantage Card and how much does PIQRAY ® cost without insurance?

Our website gives savings options to customers who wish to purchase PIQRAY®, as either a brand or generic, without the constraints of insurance. By using the Rx Advantage Card, users can save up to 90% on the cost of their medication. The card can be used at over 65,000 pharmacies nationwide, across America. Even if you are insured, in most cases the cash price will be significantly cheaper than your existing co-pay. NowPatient is able to negotiate discounts on bulk drug purchases with pharmacy owners meaning you can access lower medication prices at nearby pharmacies using our card that can be conveniently stored in your NowPatient account.

What will my out-of-pocket cost be for PIQRAY ® when using the Rx Advantage Card?

Your out-of-pocket (OOP) cost will effectively be the discounted cash price you pay for PIQRAY® using the Rx Advantage Card. If you are insured, your OOP expense can not be used against your plan deductible, if your plan has a deductible.

Yes. The Rx Advantage card is especially useful for people who have High-deductible health plans (HDHPs). It can be used for insured, uninsured, and underinsured persons.

Does the Rx Advantage Card work with Medicare or any other federal or state insurance plans?

No. We do not bill any federal or state insurance including Medicare Part D (standalone drug coverage) or Medicare Advantage (combined health and drug benefit). When you purchase your medication using the NowPatient Rx Advantage Card, you will be doing so out of pocket. The spend will not count towards your plan deductibles or gaps in the event you have a plan with a deductible. The out-of-pocket PIQRAY® cash price you pay can be typically cheaper than your plan copay.

Does the Rx Advantage Card work with Commercial Insurance?

We do not bill your commercial insurance. When you purchase your medication using the Rx Advantage Card, from NowPatient, you will be doing so out of your pocket. The spend will not count towards your plan deductibles or gaps in the event you have a plan with a deductible. The out-of-pocket PIQRAY® cash price you pay can be typically cheaper than your plan copay.

How do I check prices for PIQRAY ® and how do I use the Rx Advantage Card?

You can search for the prices at nearby pharmacies using our website. Simply search your medication and enter your ZIP Code and we will show you the price of your drug at nearby pharmacies. If you are happy with the quote, you need to create an account with NowPatient and generate your card. Next, simply go to the pharmacy and fill your PIQRAY® Rx. Ask the pharmacy to run the card and check the price, even if they tell you they have another card they use. Your card is stored safely in your NowPatient account.

Do I need to pay for the Rx Advantage Card?

No. The Rx Advantage prescription savings card is FREE to use and store for NowPatient users.

Is there a PIQRAY ® co-pay program?

You can check the top of the page to see if there is an option for a PIQRAY® co-pay card. Co-pay cards are programs run by pharmaceutical companies that offer you a direct way to lower your out-of-pocket costs for prescription drugs for eligible patients. The copay cards essentially allow physicians to prescribe medications that are clinically preferred.

What are the eligibility requirements for a PIQRAY ® co-pay card and how much do I have to pay?

Eligibility requirements vary between pharmaceutical companies. However, they almost all require you to be commercially insured. If you qualify there is no cost to you. It is a FREE program.

Can I enroll in the PIQRAY ® co-pay program if I have state, federal, or other government insurance?

Most likely, no. The copay card program is primarily designed for commercially or privately insured individuals. However, if you are finding it difficult to afford your medication, then there are other forms of assistance. For example, you can apply for LIS (Low Income Subsidy) or extra help is available online at SSA Medicare D Extra Help. You can also call Social Security at 1-800-772-1213 (TTY 1-800-325-0778). As well, you can look at state assistance programs like Medicaid.

Can I enroll in the PIQRAY ® co-pay program if I have no insurance?

Most likely No. However, many pharmaceutical companies offer fully funded free programs for uninsured persons. These programs are called Patient Assistance Programs (PAP) and NowPatient provides a useful resource to check program availability and eligibility.

How can I check if I am eligible for the PIQRAY ® co-pay program?

If a PIQRAY® co-pay card exists, you will see it as a savings option at the top of the page. You can select the option and it will direct you to an eligibility checker. If you qualify you will be prompted to create an account with NowPatient, from where you will be able to access the instructions on how to enroll.

How do I use the PIQRAY ® co-pay card?

Once you are enrolled into the program you will be able to download the card. When you next fill your Rx, simply present the co-pay card to the pharmacist. The Pharmacist will use the card to process and submit your claim. You will then be provided with your discount. The program cost is covered by the pharmaceutical company.

Is there a PIQRAY ® Patient Assistance Program (PAP)?

You can check the top of the page to see if there is an option for a PIQRAY patient assistance program. PAPs are programs that are run and sponsored by pharmaceutical companies. They offer uninsured, insured, or underinsured individuals access to high-cost brand-name medications, which may otherwise be unaffordable.

What are the eligibility requirements for a PIQRAY ® PAP and how much do I have to pay?

Eligibility requirements vary between pharmaceutical companies. However, they almost all require you to be uninsured, underinsured with no drug coverage, or insured but unable to afford your co-pay or co-insurance contribution. If you qualify there is no cost to you. It is a FREE program funded by the pharmaceutical company.

Can I enroll in a PIQRAY ® PAP if I have state, federal, or other government insurance?

It is possible. Some programs do not allow any insured individuals to apply, however, some programs do have exceptions. If you find that you do not qualify and are finding it difficult to afford your medication, then there are other forms of assistance. For example, you can apply for LIS (Low Income Subsidy) or extra help is available online at SSA Medicare D Extra Help. You can also call Social Security at 1-800-772-1213 (TTY 1-800-325-0778). As well, you can look at state assistance programs like Medicaid.

Can I enroll in a PIQRAY ® PAP if I have no insurance?

Yes. Most programs are open to individuals who are uninsured and meet income eligibility criteria.

How can I check if I am eligible for the PIQRAY ® PAP?

If a PIQRAY® patient assistance program exists, you will see it as a savings option at the top of the page. You can select the option and it will direct you to an eligibility checker. If you qualify you will be prompted to create an account with NowPatient, from where you will be able to access the instructions on how to enroll.

How do I use the PIQRAY ® PAP to obtain my medication?

Once you are enrolled in the program you will be advised by the pharmaceutical company how they will make supplies to you. In most cases, they will ship the medication through their nominated mail-order pharmacy, directly to you. However, depending on the nature of the medication, the pharmaceutical company may opt to provide you with a pharmacy card (which you can redeem against your medication for FREE at your nearby pharmacy) or ship the medication directly to your healthcare provider (HCP).

Refills are usually handled by the pharmaceutical company.

I am insured but I do not qualify for patient assistance or copay assistance for PIQRAY ®. Is there any other form of assistance that can help with the costs of my existing copays or co-insurance?

There are a number of resources available such as charitable foundations that may be able to provide assistance for your PIQRAY®:

Patient Access Network Foundation (PAN) assistance for PIQRAY®

If you are having trouble paying for your PIQRAY® medication due to unaffordable copays or deductibles, the Patient Access Network Foundation (PAN), may be able to assist you. To qualify for PAN assistance for PIQRAY® you will need to meet one or all of the following criteria:

  • Your income is below 400% of the federal poverty level
  • PIQRAY® is prescribed for an approved FDA indication
  • You live in and receive treatment in the United States or U.S. territories, even if you do not have U.S. citizenship
  • You have Medicare insurance coverage that covers PIQRAY®
  • If PIQRAY® is listed on PAN's list of covered medications

You can check the Patient Access Network Foundation Website for more information.

HealthWell Foundation Copay Program for PIQRAY®

If you are having trouble paying for your PIQRAY® medication due to unaffordable copays or deductibles, the HealthWell Foundation Copay Program may be able to assist you. To qualify for assistance for PIQRAY® you will need to meet the following criteria:

  • You live in and are being treated in the United States
  • You are insured and your plan covers PIQRAY®
  • If PIQRAY® is listed on the HealthWell Foundation's list of covered medications

You can check the HealthWell Foundation Website for more information.

Patient Advocate Foundation Co-Pay Relief Program for PIQRAY®

Patient Advocate Foundation's Co-Pay Relief program exists to help reduce the financial distress you or your family may face when paying for your PIQRAY® treatment. If you qualify and can demonstrate the need, the foundation will provide you with direct payment covering co-pays, co-insurance, and deductibles. To qualify for assistance for PIQRAY® you will need to meet the following criteria:

  • You must be currently insured and have coverage for PIQRAY®
  • You must have a confirmed diagnosis and treatment plan
  • You must reside and receive treatment in the United States
  • Your Income must fall at or below 3000r 4000f the Federal Poverty Guideline (FPG) with consideration for the Cost of Living Index (COLI) and number in the household
  • Applications can also be completed by contacting the program sponsor, toll-free at 866-512-3861.

You can check the Patient Advocate Foundation Website for more information.

What should I do if I take too much PIQRAY ®?

Call your doctor right away or seek immediate medical attention if your symptoms do not improve or they become worse after using PIQRAY®. You can also call 800-222-1222 to reach the American Association of Poison Control Centers or use its online resource if you think you've used too much PIQRAY®. But if you have severe symptoms, call 911 (or your local emergency number) immediately or go to the nearest emergency room.

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Medical Disclaimer

NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information in this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.

The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.

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