Key facts about Pifeltro
What is Pifeltro?
Pifeltro is the brand name for doravirine and is available as an oral tablet.
What dosages is Pifeltro available in?
Pifeltro is available as a 100 mg oral tablet.
What is Pifeltro used for?
Pifeltro is a HIV ARV and is used as HIV treatment for adults and children (who weigh around 77 lbs or more), in combination with other HIV ARVs.
How does Pifeltro work?
Pifeltro is a non-nucleoside reverse transcriptase inhibitor (NNRTI). It stops an important enzyme (reverse transcriptase), which prevents the HIV virus from making copies of itself and spreading.
How do I take Pifeltro?
Pifeltro is typically taken as 100 mg by mouth daily, with or without food.
Is it safe for me to take Pifeltro?
Pifeltro is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. Pifeltro is contraindicated when co-administered with drugs that
are strong cytochrome P450 (CYP)3A enzyme inducers as significant decreases in doravirine plasma concentrations may occur, which may decrease the effectiveness of Pifeltro.
Pifeltro Common Side Effects
Common side effects of Pifeltro:
- Dizziness
- Nausea
- Headache
- Extreme tiredness
- Diarrhea
- Strange dreams
- Stomach pain
Pifeltro Serious Side Effects
Serious side effects are rare with Pifeltro.
Effects of other drugs, drug classes and over-the-counter products on Pifeltro
The following medications may interact with Pifeltro:
- Consult the full prescribing information prior to and during treatment for important potential drug-drug interactions
Who makes Pifeltro?
Merck & Co., Inc.
Is Pifeltro safe in pregnancy?
It is not known if Pifeltro can harm your unborn baby. Pifeltro should only be used during pregnancy if the benefit to you is worth the possible risk to your baby.
There is a pregnancy exposure registry that monitors pregnancy outcomes in individuals exposed to Pifeltro during pregnancy. Healthcare providers are encouraged to register patients by calling the Antiretroviral Pregnancy Registry (APR) at 1-800-258-4263.
