Key facts about Doravirine
What dosages is Doravirine available in?
Doravirine is available as a 100 mg oral tablet.
What is Doravirine used for?
Doravirine is a HIV ARV and is used as HIV treatment for adults and children (who weigh around 77 lbs or more), in combination with other HIV ARVs.
How does Doravirine work?
Doravirine is a non-nucleoside reverse transcriptase inhibitor (NNRTI). It stops an important enzyme (reverse transcriptase), which prevents the HIV virus from making copies of itself and spreading.
How do I take Doravirine?
Doravirine is typically taken as 100 mg by mouth daily, with or without food.
Is it safe for me to take Doravirine?
Doravirine is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. Doravirine is contraindicated when co-administered with drugs that
are strong cytochrome P450 (CYP)3A enzyme inducers as significant decreases in Doravirine plasma concentrations may occur, which may decrease the effectiveness of Doravirine.
Doravirine Common Side Effects
Common side effects of Doravirine:
- Dizziness
- Nausea
- Headache
- Extreme tiredness
- Diarrhea
- Strange dreams
- Stomach pain
Doravirine Serious Side Effects
Serious side effects are rare with Doravirine.
Effects of other drugs, drug classes and over-the-counter products on Doravirine
The following medications may interact with Doravirine:
- Consult the full prescribing information prior to and during treatment for important potential drug-drug interactions
Who makes Doravirine?
Various FDA-approved generic manufacturers
Is Doravirine safe in pregnancy?
It is not known if Doravirine can harm your unborn baby. Doravirine should only be used during pregnancy if the benefit to you is worth the possible risk to your baby.
There is a pregnancy exposure registry that monitors pregnancy outcomes in individuals exposed to Doravirine during pregnancy. Healthcare providers are encouraged to register patients by calling the Antiretroviral Pregnancy Registry (APR) at 1-800-258-4263.
