Key facts about Piasky
What is Piasky?
Piasky (crovalimab-akkz) is an injectable monoclonal antibody that is used to treat a rare blood disorder called paroxysmal nocturnal hemoglobinuria (PNH).
What dosages is Piasky available in?
Piasky is available as a 340 mg/2 mL (170 mg/mL) single-dose vial.
What is Piasky used for?
Piasky is a complement C5 inhibitor that is used to treat adults and pediatric patients 13 years and older with paroxysmal nocturnal hemoglobinuria (PNH) and body weight of at least 40 kg.
How does Piasky work?
Piasky is a complement C5 inhibitor that is recycled within the bloodstream to stop blood cell destruction, a process called hemolysis.
How do I take Piasky?
Piasky is dosed based on your body weight. You will typically start with one loading dose given by IV infusion, followed by 4 additional loading doses administered by subcutaneous injection. Then you will be given a maintenance dose every 4 weeks by subcutaneous injection.
Is it safe for me to take Piasky?
Piasky is a safe and effective treatment when used for FDA approved indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. You should not take this medication if you are allergic to crovalimab or any of the inactive ingredients in the product or if you have an unresolved serious Neisseria meningitidis infection.
Piasky Common Side Effects
Common side effects of Piasky: Infusion related reactions Respiratory tract infections Viral infections Hypersensitivity reactions
Piasky Serious Side Effects
Serious side effects are rare with Piasky. Contact your healthcare provider immediately if you experience any of the following: Type III hypersensitivity reactions: joint pain, rash, fever, muscle pain, headache, fatigue, and abdominal pain
Effects of other drugs, drug classes and over-the-counter products on Piasky
The following medications may interact with Piasky: Eculizumab Ravulizumab
Who makes Piasky?
Genentech, Inc.
Is Piasky safe in pregnancy?
It is not known whether Piasky will harm your unborn baby. Talk with your healthcare provider about the risks of taking this medication if you are pregnant or plan on becoming pregnant.
