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Navin Khosla NowPatientGreen tick
Updated on 24 Apr 2024

pegfilgrastim-apgf Uses, Side Effects, Interactions, Warnings & Dosing

What dosages is pegfilgrastim-apgf available in?

What dosages is pegfilgrastim-apgf available in?

pegfilgrastim-apgf is available as a 6 mg/0.6 mL solution in a single-dose prefilled syringe.

What is pegfilgrastim-apgf used for?

What is pegfilgrastim-apgf used for?

pegfilgrastim-apgf is a colony-stimulating factor and is used for the following:

  • Infection prevention in people with certain cancers receiving anticancer medications that can cause low white blood cells (or febrile neutropenia)
  • Increase survival in people exposed to bone marrow-suppressing radiation (Neulasta only)
How does pegfilgrastim-apgf work?

How does pegfilgrastim-apgf work?

pegfilgrastim-apgf is a granulocyte colony-stimulating factor (G-CSF). It works like the G-CSF protein that you naturally have in your body. G-CSF stimulates (triggers) your bone marrow to make neutrophils, a type of white blood cell that helps your body fight infections.

How do I take pegfilgrastim-apgf?

How do I take pegfilgrastim-apgf?

Patients with cancer receiving myelosuppressive chemotherapy

  • 6 mg administered subcutaneously once per chemotherapy cycle. (2.1)
  • Do not administer between 14 days before and 24 hours after administration of cytotoxic chemotherapy
Is it safe for me to take pegfilgrastim-apgf?

Is it safe for me to take pegfilgrastim-apgf?

pegfilgrastim-apgf is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. You should not use this medication if you are a patient with a history of serious allergic reactions to human granulocyte colony-stimulating factors such as pegfilgrastim products or filgrastim products.

pegfilgrastim-apgf Common Side Effects

pegfilgrastim-apgf Common Side Effects

Common side effects of pegfilgrastim-apgf:

  • Bone pain
  • Pain in arms and legs
pegfilgrastim-apgf Serious Side Effects

pegfilgrastim-apgf Serious Side Effects

Serious side effects are rare with pegfilgrastim-apgf. Contact your healthcare provider immediately if you experience any of the following.

  • Shortness of breath or trouble breathing
  • Ruptured spleen: pain in your left upper stomach or shoulder
  • Serious allergic reaction: rash, trouble breathing, swelling of your tongue, lips, or throat
Effects of other drugs, drug classes and over-the-counter products on pegfilgrastim-apgf

Effects of other drugs, drug classes and over-the-counter products on pegfilgrastim-apgf

There are no major drug interactions listed for pegfilgrastim-apgf. However, always let your physician and pharmacist know about any other medications or supplements (including prescribed and over-the-counter medications, vitamins, and dietary or herbal supplements) that you are currently taking.

Who makes pegfilgrastim-apgf?

Who makes pegfilgrastim-apgf?

Various FDA-approved generic manufacturers

Is pegfilgrastim-apgf safe in pregnancy?

Is pegfilgrastim-apgf safe in pregnancy?

It is not known if pegfilgrastim-apgf harms your unborn baby. pegfilgrastim-apgf should be given to a pregnant woman only if clearly needed. Talk to your doctor about stopping NORPACE CR if you
are pregnant or planning to become pregnant.


What to do if you missed your pegfilgrastim-apgf dose

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NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.

The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.

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