OFEV
NowPatient helps you obtain your OFEV prescription for free or at low-cost. Drug savings programs are suitable for individuals who are insured, don't have insurance or are underinsured and can't afford your medicine.
Manufactured by Boehringer Ingelheim Pharmaceuticals, Inc.
*You can pay as little as $0 per fill using Drug Coupons or Patient Assistance Programs. Subject to applicability & eligibility requirements.
This content is intended for US audiences only
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OFEV key facts
What is OFEV?
OFEV is the brand name for nintedanib and is available as an oral capsule.
What dosages is OFEV available in?
OFEV is available as a 100 mg and 150 mg oral capsule.
What is OFEV used for?
OFEV is a tyrosine kinase inhibitor and is used for the following:
- Idiopathic pulmonary fibrosis
- Progressive fibrosing ILD
- Systemic sclerosis-associated ILD
How does OFEV work?
OFEV is a tyrosine kinase inhibitor, meaning it blocks a protein called tyrosine kinase. This protein is involved in making scar tissue in your lungs. By blocking its activity, OFEV can treat scarring in the lungs from certain types of interstitial lung disease. This helps lower the lung symptoms you have, such as shortness of breath and cough.
How do I take OFEV?
- OFEV is typically dosed as 150 mg taken by mouth twice daily, 12 hours apart
- Your dose will be different if you have liver problems
Is it safe for me to take OFEV?
OFEV is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you.
OFEV Common Side Effects
Common side effects of OFEV:
- Diarrhea
- Nausea
- Stomach pain
- Vomiting
- Elevated liver enzymes
- Fatigue
- Weight loss
- Headache
- Fever
- Back pain
- Dizziness
- High blood pressure
OFEV Serious Side Effects
Serious side effects are rare with OFEV. Contact your healthcare provider immediately if you experience any of the following.
- Liver problems or liver failure: yellowing of your skin or the whites of your eyes, confusion, fatigue, low appetite, nausea, stomach discomfort, vomiting
- Heart attack: chest pain, short of breath, pain in the jaw, neck, or back, feeling weak or light-headed
- Blood clots in other parts of the body: chest pain, difficulty breathing, weakness, numbness or tingling sensation in arms and legs
- Serious bleeds: bleeds that are difficult to stop, bruises that don’t go away, weakness, tiredness, headaches, dizziness, bloody stool or blood in the urine
- Severe damage to stomach or intestines: sudden and severe pain or tenderness in stomach area, bloating, nausea, vomiting, bleeding in the rectum, change in appetite
Effects of other drugs, drug classes and over-the-counter products on OFEV
The following medications may interact with OFEV:
- Coadministration of P-gp and CYP3A4 inhibitors may increase nintedanib exposure
- Monitor patients closely for tolerability of OFEV
Who makes OFEV?
Boehringer Ingelheim Pharmaceuticals, Inc.
Is OFEV safe in pregnancy?
Based on findings from animal studies and its mechanism of action, OFEV can cause fetal harm when administered to a pregnant woman. You should avoid becoming pregnant while receiving treatment with OFEV and use highly effective contraception at initiation of, during treatment, and at least 3 months after the last dose of OFEV.
The FDA's medical product safety reporting program for health professionals, patients and consumers.
Learn more about reporting side effects in the USDrug Savings Guide
A practical guide to saving money and receiving support with prescription costs
How can NowPatient help me to lower the cost of my OFEV prescription?
After you create a FREE account with NowPatient, you will have access to 4 programs that can help lower the cost of your OFEV prescription
Applicability to each program will be dependent on your insurance status.
How do the NowPatient OFEV savings programs work?
After you have created your FREE account with NowPatient, you can access the various programs from your account dashboard. Each program has clear instructions on how to check your eligibility. You can see how the process works by clicking on the feature link below and seeing the ‘How it works’ steps.
Drug Coupon and Patient Assistance Programs require an eligibility quiz to be completed.
Are the NowPatient OFEV savings programs suitable for everyone, regardless of insurance status?
No. Each program has its own eligibility and applicability requirements. The table below shows if a program is available to you, based on your insurance status.
| Rx Advantage Card* for OFEV | Canadian Prescription Savings* for OFEV | OFEV Drug Coupon* | OFEV Patient Assistance Program* | |
| Insured (federal, state or government) | Available | Available | Not Available | Available If Offered by Pharmaceutical Company |
| Insured (Commercial or Private) | Available | Available | Available If Offered by Pharmaceutical Company | Available If Offered by Pharmaceutical Company |
| Uninsured | Available | Available | Not Available | Available If Offered by Pharmaceutical Company |
| Insured but without pharmacy benefit or drug coverage | Available | Available | Not Available | Available If Offered by Pharmaceutical Company |
*This is not insurance.
Are the NowPatient drug savings programs suitable for brand and generic versions of OFEV?
No. Each program has applicability requirements. Please see below
| Rx Advantage Card* for OFEV | Canadian Prescription Savings* for OFEV | OFEV Drug Coupon* | OFEV Patient Assistance Program* | |
| Brand | Yes | Yes | Yes, If Offered by Pharmaceutical Company | Yes, If Offered by Pharmaceutical Company |
| Generic | Yes | Yes | No | No |
*This is not insurance.
If you have Medicare Part D or Medicare Advantage and none of the OFEV savings options are applicable or affordable for me, what can you do?
If you are insured with Medicare and the OFEV drug savings options are not applicable to you and still remain unaffordable, then you can check Medicaid eligibility in your state by following the instructions at HealthCare.gov.
The government site is easy to use and after you have selected your state, it will navigate you to the appropriate contact point to make the application. State Medicaid programs may cover the full cost of your medication.
People who qualify for both Medicare and Medicaid are called ‘dual eligibles’.
If you are denied Medicaid for OFEV, and you are still unable to afford your copay or co-insurance element (for example if you are in the coverage gap or Donut Hole) then you may be eligible for a federal support program like Low Income Subsidy. To be eligible for Low Income Subsidy, you need to be a resident in one of the 50 States or the District of Columbia. You can check eligibility online at SSA Medicare D Extra Help. You can also call Social Security at 1-800-772-1213 (TTY 1-800-325-0778).
I am uninsured or underinsured and none of the OFEV prescription saving options are applicable or affordable for me, what can I do?
If you are uninsured or underinsured (for example, OFEV is not covered by your plan) and the drug savings options are not applicable or still unaffordable, then you can check Medicaid eligibility in your state by following the instructions at HealthCare.gov.
The government site is easy to use and you can select your state and it will navigate you to the appropriate contact point to make the application. State Medicaid programs may cover the full cost of your medication.
If you are denied and all else fails, and if you have been prescribed OFEV for an FDA-approved indication, you can call the pharmaceutical company to see if they have any other assistance programs.
I am commercially or privately insured and none of the OFEV prescription saving options are applicable or affordable for me, what can I do?
If your medication is not covered by your plan, you can you can appeal your insurance company’s decision. Sometimes, a formal appeal can result in the drug being covered if it is deemed medically necessary.
If you cannot afford your copay, then you can check Medicaid eligibility in your state by following the instructions at HealthCare.gov.
However, being privately insured might complicate your eligibility for Medicaid, as having private insurance may be considered in the financial eligibility assessment.
The government site is easy to use and you can select your state and it will navigate you to the appropriate contact point to make the application. If you qualify, state Medicaid may cover the full cost of your medication.
If I have federal, state or commercial insurance and none of the OFEV prescription saving options are applicable or affordable for me, are there any other support organisations that can help me with my co-insurance or copay?
If you have already tried Medicaid and received a denial letter or if you are insured with Medicare and have been denied Low-Income Subsidy, then you can try one of the following organizational support programs:
1. Patient Access Network Foundation (PAN) assistance for OFEV
If you are having trouble paying for your OFEV medication due to unaffordable copays or deductibles, the Patient Access Network Foundation (PAN), may be able to assist you. To qualify for PAN assistance for OFEV you will need to meet one or all of the following criteria:
- Your income is below 400% of the federal poverty level
- OFEV is prescribed for an approved FDA indication
- You live in and receive treatment in the United States or U.S. territories, even if you do not have U.S. citizenship
- You have Medicare insurance coverage that covers OFEV
- If OFEV is listed on PAN’s list of covered medications
You can check the Patient Access Network Foundation Website for more information.
2. HealthWell Foundation Copay Program for OFEV
If you are having trouble paying for your OFEV medication due to unaffordable copays or deductibles, the HealthWell Foundation Copay Program may be able to assist you. To qualify for assistance for OFEV you will need to meet the following criteria:
- You live in and are being treated in the United States
- You are insured and your plan covers OFEV
- If OFEV is listed on the HealthWell Foundation’s list of covered medications
You can check the HealthWell Foundation Website for more information.
3. Patient Advocate Foundation Co-Pay Relief Program for OFEV
Patient Advocate Foundation’s Co-Pay Relief program exists to help reduce the financial distress you or your family may face when paying for your OFEV treatment. If you qualify and can demonstrate the need, the foundation will provide you with direct payment covering co-pays, co-insurance, and deductibles. To qualify for assistance for OFEV you will need to meet the following criteria:
- You must be currently insured and have coverage for OFEV
- You must have a confirmed diagnosis and treatment plan
- You must reside and receive treatment in the United States
- Your Income must fall at or below 300% or 400% of the Federal Poverty Guideline (FPG) with consideration for the Cost of Living Index (COLI) and number in the household
- Applications can also be completed by contacting the program sponsor, toll-free at 866-512-3861.
You can check the Patient Advocate Foundation Website for more information.
Medical Disclaimer
NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.
The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.
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