Key facts about Ofatumumab
What dosages is Ofatumumab available in?
Ofatumumab is available as a 20 mg/0.4 mL solution in a single-dose prefilled Sensoready Pen and a 20 mg/0.4 mL solution in a single-dose prefilled syringe.
What is Ofatumumab used for?
Ofatumumab is a monoclonal antibody and is used to treat relapsing forms of multiple sclerosis (MS).
How does Ofatumumab work?
Ofatumumab is a monoclonal antibody. It’s not exactly known how the medication works. But it’s thought to treat MS by preventing certain immune cells in your body from attacking the coverings on your nerve cells by mistake. This might help ease symptoms of MS.
How do I take Ofatumumab?
The typical starting dose of Ofatumumab is to inject 20 mg of Ofatumumab under the skin once a week for 3 weeks. Starting from week 4, the typical maintenance dose is to inject 20 mg once a month.
Is it safe for me to take Ofatumumab?
Ofatumumab is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. You should not use this medication if you have an active HBV infection.
Ofatumumab Common Side Effects
Common side effects of Ofatumumab:
- Sore throat, runny nose, and other symptoms of respiratory tract infections
- Fever, headaches, and other injection-related reactions
- Headache
- Pain, redness, and other reactions at the injection site
- Pain while urinating and other symptoms of an urinary tract infections
Ofatumumab Serious Side Effects
Serious side effects are rare with Ofatumumab. Contact your healthcare provider immediately if you experience any of the following.
- Serious infections: fever, tiredness, chills, cough, trouble breathing
Effects of other drugs, drug classes and over-the-counter products on Ofatumumab
The following medications may interact with Ofatumumab:
- Concomitant usage of Ofatumumab with immunosuppressant drugs, including systemic corticosteroids, may increase the risk of infection Consider the risk of additive immune system effects when coadministering immunosuppressive therapies with Ofatumumab
- When switching from therapies with immune effects, the duration and mechanism of action of these therapies should be taken into account because of potential additive immunosuppressive effects when initiating Ofatumumab
Who makes Ofatumumab?
Various FDA-approved generic manufacturers
Is Ofatumumab safe in pregnancy?
It is not known if Ofatumumab will harm your unborn baby. Females who can become pregnant should use birth control (contraception) during treatment with Ofatumumab and for 6 months after your last treatment. Talk with your healthcare provider about what birth control method is right for you during this time.
