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Kesimpta is the brand name for ofatumumab and is available as a subcutaneous injection.

Kesimpta is available as a 20 mg/0.4 mL solution in a single-dose prefilled Sensoready Pen and a 20 mg/0.4 mL solution in a single-dose prefilled syringe.

Kesimpta is a monoclonal antibody and is used to treat relapsing forms of multiple sclerosis (MS).

Kesimpta is a monoclonal antibody. It’s not exactly known how the medication works. But it’s thought to treat MS by preventing certain immune cells in your body from attacking the coverings on your nerve cells by mistake. This might help ease symptoms of MS.

The typical starting dose of Kesimpta is to inject 20 mg of Kesimpta (ofatumumab) under the skin once a week for 3 weeks. Starting from week 4, the typical maintenance dose is to inject 20 mg once a month.

Kesimpta is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. You should not use this medication if you have an active HBV infection.

Common side effects of Kesimpta:

• Sore throat, runny nose, and other symptoms of respiratory tract infections
• Fever, headaches, and other injection-related reactions
• Headache
• Pain, redness, and other reactions at the injection site
• Pain while urinating and other symptoms of an urinary tract infections

Serious side effects are rare with Kesimpta. Contact your healthcare provider immediately if you experience any of the following.

• Serious infections: fever, tiredness, chills, cough, trouble breathing

The following medications may interact with Kesimpta:

• Concomitant usage of Kesimpta with immunosuppressant drugs, including systemic corticosteroids, may increase the risk of infection Consider the risk of additive immune system effects when coadministering immunosuppressive therapies with Kesimpta
• When switching from therapies with immune effects, the duration and mechanism of action of these therapies should be taken into account because of potential additive immunosuppressive effects when initiating Kesimpta

Novartis Pharmaceuticals

It is not known if Kesimpta will harm your unborn baby. Females who can become pregnant should use birth control (contraception) during treatment with Kesimpta and for 6 months after your last treatment. Talk with your healthcare provider about what birth control method is right for you during this time.

• Ofatumumab