Key facts about Nexviazyme
What is Nexviazyme?
Nexviazyme is the brand name for avalglucosidase alfa-ngpt and is available as an intravenous infusion.
What dosages is Nexviazyme available in?
Nexviazyme is available as 100 mg of avalglucosidase alfa-ngpt in a single-dose vial.
What is Nexviazyme used for?
Nexviazyme is a type of enzyme replacement therapy used to treat late-onset Pompe disease (LOPD).
How does Nexviazyme work?
Nexviazyme is a hydrolytic lysosomal glycogen-specific enzyme. In Pompe disease, you’re missing an enzyme in your body called acid alpha-glucosidase (GAA). Without this enzyme, your body isn’t able to break down glycogen into sugar to use as a source of energy. Nexviazyme serves as a replacement for GAA, which allows your body to convert glycogen into sugar to use for energy.
How do I take Nexviazyme?
The typical dose of Nexviazyme is based on your body weight and will be calculated by your provider. It will then be given as an IV infusion every 2 weeks.
Is it safe for me to take Nexviazyme?
Nexviazyme is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you.
Nexviazyme Common Side Effects
Common side effects of Nexviazyme:
- Headache
- Fatigue
- Diarrhea
- Nausea
- Joint pain
- Muscle pain
- Dizziness
- Itchy skin
- Vomiting
- Shortness of breath or trouble breathing
- Numb or tingling sensation
- Skin redness
- Rash
Nexviazyme Serious Side Effects
Serious side effects are rare with Nexviazyme. Contact your healthcare provider immediately if you experience any of the following:
- Allergic reactions: hives, rash, blisters, skin reddening, swelling of the lips or tongue, difficulty breathing
Effects of other drugs, drug classes and over-the-counter products on Nexviazyme
There are no major drug interactions listed for this medication. However, always let your physician and pharmacist know about any other medications or supplements (including prescribed and over-the-counter medications, vitamins, and dietary or herbal supplements) that you are currently taking.
Who makes Nexviazyme?
Sanofi-Aventis U.S.
Is Nexviazyme safe in pregnancy?
It is not known whether this medication is safe for you and your unborn baby during pregnancy. Talk to your doctor if you are already pregnant or if you have plans on becoming pregnant. They will recommend what is best for you.
