Used for Birth Control

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Manufactured by Bayer Healthcare

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NATAZIA Uses, Side Effects, Interactions, Warnings & Dosing

What is NATAZIA?

What is NATAZIA?

NATAZIA is the brand name for estradiol valerate and estradiol valerate/dienogest oral tablets.

What dosages is NATAZIA available in?

What dosages is NATAZIA available in?

NATAZIA is available as a 28 day pack that contains 26 active tablets and 2 placebo tablets.

What is NATAZIA used for?

What is NATAZIA used for?

NATAZIA is an estrogen/progestin combination that is used:
To prevent pregnancy Heavy period bleeding not due to infection, bleeding problems, or other specific health conditions

How does NATAZIA work?

How does NATAZIA work?

NATAZIA is a combined contraceptive that contains two hormones: estradiol valerate (an estrogen) and dienogest (a progestin). Both hormones work together to prevent pregnancy by:

  • Suppressing ovulation (release of an egg from the ovary)
  • Changing cervical mucus to block sperm movement
  • Creating an unfriendly environment for the fertilized egg by changing the lining in the uterus. These hormones thin the lining of the uterus, which can help reduce period bleeding in females who experience heavy bleeding
How do I take NATAZIA?

How do I take NATAZIA?

NATAZIA comes in a 28-day pack. There are 26 active tablets and they contain different dosages of dienogest and ethinyl valerate. There are also 2 placebo tablets and they don’t contain any active medications.

  • Day 1 through 2: 3 mg ethinyl valerate only
  • Day 3 through 7: 2 mg of dienogest and 2 mg ethinyl valerate
  • Day 8 through 24: 3 mg of dienogest and 2 mg ethinyl valerate
  • Day 25 through 26: 1 mg ethinyl valerate only
  • Day 27 through 28: Placebo tablets, no active medication

The typical dose is 1 tablet by mouth at the same time every day. Tablets must be taken in the order instructed on the blister pack.

Is it safe for me to take NATAZIA?

Is it safe for me to take NATAZIA?

NATAZIA is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. You should not use this medication if you have any of the following.

  • A high risk of arterial or venous thrombotic diseases
  • Undiagnosed abnormal uterine bleeding
  • Breast cancer
  • Liver tumors or liver disease
  • Pregnancy
NATAZIA Common Side Effects

NATAZIA Common Side Effects

Common side effects of NATAZIA:

  • Headache
  • Breast pain, discomfort, or tenderness
  • Irregular vaginal bleeding
  • Nausea or vomiting
  • Acne
  • Mood changes
  • Weight gain
NATAZIA Serious Side Effects

NATAZIA Serious Side Effects

Serious side effects are rare with NATAZIA. Contact your healthcare provider immediately if you experience any of the following.

  • Heart attack: chest pain, stomach discomfort, sweating, nausea, dizziness
  • Stroke: sudden numbness or weakness in the arm, leg, or face, confusion, trouble seeing, headache, difficulty walking
  • Deep vein thrombosis (blood clot in the leg): leg cramp, swelling, pain, muscle tightness
  • Pulmonary embolism (blood clot in the lung): cough, chest pain, trouble breathing, racing heart
  • Serious liver problems: yellowing of the skin or the whites of the eyes, tiredness, stomach pain
  • Ruptured ovarian cyst: stomach pain, nausea, vomiting, fever, dizziness, vaginal bleeding
Effects of other drugs, drug classes and over-the-counter products on NATAZIA

Effects of other drugs, drug classes and over-the-counter products on NATAZIA

The following medications may interact with NATAZIA:

  • Drugs or herbal products that induce certain enzymes (for example CYP3A4) may decrease the effectiveness of COCs or increase breakthrough bleeding
  • Counsel patients to use a back-up or alternative method of contraception when enzyme inducers are used with COCs
Who makes NATAZIA?

Who makes NATAZIA?

Bayer Healthcare

Is NATAZIA safe in pregnancy?

Is NATAZIA safe in pregnancy?

NATAZIA is not indicated during pregnancy. If pregnancy occurs during treatment let your healthcare provider know immediately.


What to do if you missed your NATAZIA dose

The FDA's medical product safety reporting program for health professionals, patients and consumers.

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NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.

The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.

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