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estradiol valerate and estradiol valerate/dienogest

estradiol valerate and estradiol valerate/dienogest

Used for Birth Control

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Manufactured by various FDA-approved generic manufacturers.

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Updated on 24 Apr 2024

estradiol valerate and estradiol valerate/dienogest Uses, Side Effects, Interactions, Warnings & Dosing

What dosages is estradiol valerate and estradiol valerate/dienogest available in?

What dosages is estradiol valerate and estradiol valerate/dienogest available in?

estradiol valerate and estradiol valerate/dienogest is available as a 28 day pack that contains 26 active tablets and 2 placebo tablets.

What is estradiol valerate and estradiol valerate/dienogest used for?

What is estradiol valerate and estradiol valerate/dienogest used for?

estradiol valerate and estradiol valerate/dienogest is an estrogen/progestin combination that is used:
To prevent pregnancy Heavy period bleeding not due to infection, bleeding problems, or other specific health conditions

How does estradiol valerate and estradiol valerate/dienogest work?

How does estradiol valerate and estradiol valerate/dienogest work?

estradiol valerate and estradiol valerate/dienogest is a combined contraceptive that contains two hormones: estradiol valerate (an estrogen) and dienogest (a progestin). Both hormones work together to prevent pregnancy by:

  • Suppressing ovulation (release of an egg from the ovary)
  • Changing cervical mucus to block sperm movement
  • Creating an unfriendly environment for the fertilized egg by changing the lining in the uterus. These hormones thin the lining of the uterus, which can help reduce period bleeding in females who experience heavy bleeding
How do I take estradiol valerate and estradiol valerate/dienogest?

How do I take estradiol valerate and estradiol valerate/dienogest?

estradiol valerate and estradiol valerate/dienogest comes in a 28-day pack. There are 26 active tablets and they contain different dosages of dienogest and ethinyl valerate. There are also 2 placebo tablets and they don’t contain any active medications.

  • Day 1 through 2: 3 mg ethinyl valerate only
  • Day 3 through 7: 2 mg of dienogest and 2 mg ethinyl valerate
  • Day 8 through 24: 3 mg of dienogest and 2 mg ethinyl valerate
  • Day 25 through 26: 1 mg ethinyl valerate only
  • Day 27 through 28: Placebo tablets, no active medication

The typical dose is 1 tablet by mouth at the same time every day. Tablets must be taken in the order instructed on the blister pack.

Is it safe for me to take estradiol valerate and estradiol valerate/dienogest?

Is it safe for me to take estradiol valerate and estradiol valerate/dienogest?

estradiol valerate and estradiol valerate/dienogest is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. You should not use this medication if you have any of the following.

  • A high risk of arterial or venous thrombotic diseases
  • Undiagnosed abnormal uterine bleeding
  • Breast cancer
  • Liver tumors or liver disease
  • Pregnancy
estradiol valerate and estradiol valerate/dienogest Common Side Effects

estradiol valerate and estradiol valerate/dienogest Common Side Effects

Common side effects of estradiol valerate and estradiol valerate/dienogest:

  • Headache
  • Breast pain, discomfort, or tenderness
  • Irregular vaginal bleeding
  • Nausea or vomiting
  • Acne
  • Mood changes
  • Weight gain
estradiol valerate and estradiol valerate/dienogest Serious Side Effects

estradiol valerate and estradiol valerate/dienogest Serious Side Effects

Serious side effects are rare with estradiol valerate and estradiol valerate/dienogest. Contact your healthcare provider immediately if you experience any of the following.

  • Heart attack: chest pain, stomach discomfort, sweating, nausea, dizziness
  • Stroke: sudden numbness or weakness in the arm, leg, or face, confusion, trouble seeing, headache, difficulty walking
  • Deep vein thrombosis (blood clot in the leg): leg cramp, swelling, pain, muscle tightness
  • Pulmonary embolism (blood clot in the lung): cough, chest pain, trouble breathing, racing heart
  • Serious liver problems: yellowing of the skin or the whites of the eyes, tiredness, stomach pain
  • Ruptured ovarian cyst: stomach pain, nausea, vomiting, fever, dizziness, vaginal bleeding
Effects of other drugs, drug classes and over-the-counter products on estradiol valerate and estradiol valerate/dienogest

Effects of other drugs, drug classes and over-the-counter products on estradiol valerate and estradiol valerate/dienogest

The following medications may interact with estradiol valerate and estradiol valerate/dienogest:

  • Drugs or herbal products that induce certain enzymes (for example CYP3A4) may decrease the effectiveness of COCs or increase breakthrough bleeding
  • Counsel patients to use a back-up or alternative method of contraception when enzyme inducers are used with COCs
Who makes estradiol valerate and estradiol valerate/dienogest?

Who makes estradiol valerate and estradiol valerate/dienogest?

Various FDA-approved generic manufacturers

Is estradiol valerate and estradiol valerate/dienogest safe in pregnancy?

Is estradiol valerate and estradiol valerate/dienogest safe in pregnancy?

estradiol valerate and estradiol valerate/dienogest is not indicated during pregnancy. If pregnancy occurs during treatment let your healthcare provider know immediately.

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What to do if you missed your estradiol valerate and estradiol valerate/dienogest dose

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NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.

The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.

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