Key facts about Naloxone HCL
What dosages is Naloxone HCL available in?
Naloxone HCL is available as a nasal spray that contains 4 mg of naloxone hydrochloride per 0.1 mL.
What is Naloxone HCL used for?
Naloxone HCL is a life-saving medication that’s used to reverse the effects of an opioid overdose.
How does Naloxone HCL work?
Naloxone HCL is an opioid antagonist.It works by blocking opioids from binding to the opioid receptors. Doing this reverses the symptoms of an opioid overdose, such as slowed breathing, extreme sleepiness, and low blood pressure.
How do I take Naloxone HCL?
You should call 911 first, then give Naloxone HCL. The usual dose is 1 spray in one nostril as a single dose. If the person doesn’t respond after 2 to 3 minutes, spray a second dose in the other nostril using a new nasal spray. Continue to repeat the dose with a new nasal spray every 2 to 3 minutes if the person doesn’t respond, until medical help arrives.
Is it safe for me to take Naloxone HCL?
Naloxone HCL is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. You should not use this medication in the following:
- Hypersensitivity to naloxone hydrochloride
Naloxone HCL Common Side Effects
Common side effects of Naloxone HCL:
- Temporary higher blood pressure
- Headache
- Dry nose
- Nasal congestion
- Swollen or inflamed nose
- Nose pain
Naloxone HCL Serious Side Effects
Serious side effects are rare with Naloxone HCL. Contact your healthcare provider immediately if you experience any of the following:
- Opioid withdrawal symptoms: aggressive behavior, pain, fast heartbeat, sweating, irritability, vomiting
Effects of other drugs, drug classes and over-the-counter products on Naloxone HCL
There are no major drug interactions listed for this medication. However, always let your physician and pharmacist know about any other medications or supplements (including prescribed and over-the-counter medications, vitamins, and dietary or herbal supplements) that you are currently taking.
Who makes Naloxone HCL?
Various FDA-approved generic manufacturers
Is Naloxone HCL safe in pregnancy?
It is not known whether this medication is safe for you and your unborn baby during pregnancy. Talk to your doctor if you are already pregnant or if you have plans on becoming pregnant. They will recommend what is best for you.













