Key facts about Nafarelin Acetate
What dosages is Nafarelin Acetate available in?
Nafarelin Acetate is available as a 2 mg/ml nasal solution.
What is Nafarelin Acetate used for?
Nafarelin Acetate is a gonadotropin-releasing hormone (GnRH) agonist that is used to treat endometriosis in adults.
How does Nafarelin Acetate work?
Nafarelin Acetate is a gonadotropin-releasing hormone (GnRH) agonist, meaning that it acts like GnRH. GnRH is a hormone that regulates how much sex hormones gets released into your body. One of these sex hormones is estrogen, which plays a role in endometrial tissue growth. By acting like GnRH, Nafarelin Acetate stops the body from releasing estrogen over time. This helps shrink endometrial tissue outside the uterus and relieve pain from endometriosis.
How do I take Nafarelin Acetate?
Nafarelin Acetate is typically dosed as 1 spray into one nostril in the morning and 1 spray into the other nostril in the evening, separated by about 12 hours. If needed, your provider might raise your dose to 1 spray into each nostril in the morning and evening (a total of 4 sprays per day). You typically start treatment with Nafarelin Acetate between days 2 and 4 of your menstrual cycle. The recommended length of treatment is 6 months.
Is it safe for me to take Nafarelin Acetate?
Nafarelin Acetate is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. You should not use this medication in the following:
- Hypersensitivity to GnRH, GnRH agonist analogs or any of the excipients in Nafarelin Acetate
- Undiagnosed abnormal vaginal bleeding
- Use in pregnancy or in women who may become pregnant while receiving the drug
Nafarelin Acetate Common Side Effects
Common side effects of Nafarelin Acetate:
- Hot flashes
- Lower sex drive
- Vaginal dryness
- Headaches
- Mood swings
- Acne
Nafarelin Acetate Serious Side Effects
Serious side effects are rare with Nafarelin Acetate.
Effects of other drugs, drug classes and over-the-counter products on Nafarelin Acetate
The following medications may interact with Nafarelin Acetate:
Who makes Nafarelin Acetate?
Various FDA-approved generic manufacturers
Is Nafarelin Acetate safe in pregnancy?
No pharmacokinetic-based drug-drug interaction studies have been conducted with Nafarelin Acetate. Tell your healthcare provider right away if you are or if you become pregnant.













