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MEDICAL INFORMATION
Mobocertinib Key Facts
What dosages is Mobocertinib available in?
Mobocertinib is available as a 40 mg oral capsule.
What is Mobocertinib used for?
Mobocertinib is a tyrosine kinase inhibitor and is used to treat locally advanced or metastatic non-small cell lung cancer (NSCLC) with EGFR exon 20 insertion mutations in people who have previously had chemotherapy.
How does Mobocertinib work?
Mobocertinib works by blocking tyrosine kinases in cancer cells. Tyrosine kinases are proteins that tell cancer cells to grow and divide. By stopping these proteins, Mobocertinib helps treat NSCLC by aiming to slow down cancer growth.
How do I take Mobocertinib?
Mobocertinib is typically started at 160 mg (4 capsules) by mouth once daily with or without food. Your dose might be lowered if you experience certain side effects or if you’re taking certain medications.
Is it safe for me to take Mobocertinib?
Mobocertinib is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you.
Mobocertinib Common Side Effects
Common side effects of Mobocertinib:
- Diarrhea
- Skin rash
- Mouth sores
- Vomiting
- Loss of appetite
- Fingernail and toenail infections
- Nausea
- Muscle or bone pain
- Dry skin
- Fatigue
- Itchiness
- Cough
- Weight loss
Mobocertinib Serious Side Effects
Serious side effects are rare with Mobocertinib. Contact your healthcare provider immediately if you experience any of the following.
- Abnormal heart rhythm: lightheadedness, dizziness, feeling faint
- Heart failure: shortness of breath, cough or wheezing, fast heart rate, swelling (edema), weight gain
- Lung damage: cough, trouble breathing, chest pain
Severe diarrhea
Effects of other drugs, drug classes and over-the-counter products on Mobocertinib
The following medications may interact with Mobocertinib:
- CYP3A Inhibitors: Avoid concomitant use of Mobocertinib with strong or moderate CYP3A inhibitors. If concomitant use of a moderate
- CYP3A inhibitor is unavoidable, reduce the dose of Mobocertinib
- CYP3A Inducers: Avoid concomitant use of Mobocertinib with strong or moderate CYP3A inducers
Who makes Mobocertinib?
Various FDA-approved generic manufacturers
Is Mobocertinib safe in pregnancy?
Mobocertinib can harm your unborn baby. If you can become pregnant, your healthcare provider should do a pregnancy test before you start treatment with Mobocertinib. You should use an effective form of non-hormonal birth control during treatment and for 1 month after your last dose of Mobocertinib. Birth control pills (oral contraceptives) and other hormonal forms of birth control may not work as well during treatment with Mobocertinib. Tell your healthcare provider right away if you become pregnant or think you may be pregnant during
treatment with Mobocertinib. For males who have female partners who are able to become pregnant, you should use effective birth control during treatment and for 1 week after your last dose of Mobocertinib.
What is the brand name for Mobocertinib?
Medical Disclaimer
NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.
The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.
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