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MEDICAL INFORMATION
Mepron Key Facts
What is Mepron?
Mepron is the brand name for atovaquone and is available as an oral suspension.
What dosages is Mepron available in?
Mepron is available as a 750 mg/5 ml oral suspension.
What is Mepron used for?
Mepron is an antiprotozoal that is used for the treatment and prevention of pneumonia caused by the Pneumocystis jirovecii fungus. This medication is used when people cannot tolerate the first-choice medication, trimethoprim-sulfamethoxazole.
How does Mepron work?
Mepron is an antifungal medication. It prevents and treats the fungus, Pneumocystis jirovecii, from reproducing and causing pneumonia in your body.
How do I take Mepron?
Mepron is dosed as 1500 mg (10 mL) by mouth once daily with food for pneumonia prevention and 750 mg (5 mL) by mouth twice daily with food for 21 days for pneumonia treatment.
Is it safe for me to take Mepron?
Mepron is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. You should not use this medication if you have a known serious allergic/hypersensitivity reaction (e.g., angioedema, bronchospasm, throat tightness, urticaria) to atovaquone or any of the components of Mepron.
Mepron Common Side Effects
Common side effects of Mepron:
- Diarrhea
- Rash
- Headache
- Nausea
- Fever
- Vomiting
Mepron Serious Side Effects
Serious side effects are rare with Mepron. Contact your healthcare provider immediately if you experience any of the following.
- Allergic reaction
Effects of other drugs, drug classes and over-the-counter products on Mepron
The following medications may interact with Mepron:
- Concomitant administration of rifampin or rifabutin reduces atovaquone concentrations; concomitant use with Mepron oral suspension is not recommended
- Concomitant administration of tetracycline reduces atovaquone concentrations; use caution when coadministering. Monitor patients for potential loss of efficacy of Mepron if coadministration of tetracycline is necessary
- Concomitant administration with metoclopramide reduces atovaquone concentrations; administer concomitantly only if other antiemetics are not available.
- Concomitant administration of indinavir reduces indinavir trough concentrations; use caution when coadministering. Monitor patients for potential loss of efficacy of indinavir if coadministration is necessary
Who makes Mepron?
GlaxoSmithKline
Is Mepron safe in pregnancy?
It is not known if Mepron will harm your unborn baby. You should talk to your healthcare provider before taking this medication if you are pregnant.
What is the generic name for Mepron?
Medical Disclaimer
NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.
The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.
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