Key facts about Lupron Depot-Ped
What is Lupron Depot-Ped?
Lupron Depot-Ped is the brand name for leuprolide acetate and is available as an intramuscular injection.
What dosages is Lupron Depot-Ped available in?
Lupron Depot-Ped is available as a 7.5 mg, 11.25 mg, 15 mg, 30 mg, or 45 mg single-dose, prefilled dual-chamber syringe with diluent.
What is Lupron Depot-Ped used for?
Lupron Depot-Ped is a GnRH agonist that is used to prevent precocious puberty (puberty that starts at an early age).
How does Lupron Depot-Ped work?
Lupron Depot-Ped is a gonadotropin-releasing hormone (GnRH) agonist, which is a synthetic (man-made) hormone similar to the GnRH your body naturally makes. It lowers reproductive hormone levels, estrogen and testosterone, which are a part of the process of puberty.
How do I take Lupron Depot-Ped?
Lupron Depot-Ped is given by your child’s healthcare provider. The dose is based on your child’s body weight and is injected into the thigh, shoulder, or buttock muscle. It can be given once every month or once every 3 months.
Is it safe for me to take Lupron Depot-Ped?
Lupron Depot-PedLupron Depot-Ped is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. You should not use this medication in the following:
Lupron Depot-Ped Common Side Effects
Common side effects of Lupron Depot-Ped:
- Injection site reactions
- Mood changes
- General pain
- Headache
- Acne
- Serious skin rash
- Swelling of vagina (vaginitis), vaginal bleeding, and vaginal discharge/fluids
Lupron Depot-Ped Serious Side Effects
Serious side effects are rare with Lupron Depot-Ped. Contact your healthcare provider immediately if you experience any of the following:
- Seizures
- Severe cutaneous adverse reactions (SCARs): Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN)
- Increased intracranial pressure
Effects of other drugs, drug classes and over-the-counter products on Lupron Depot-Ped
The following medications may interact with Lupron Depot-Ped:
- Certain tests for pituitary and gonadal function
Who makes Lupron Depot-Ped?
AbbVie Inc.
Is Lupron Depot-Ped safe in pregnancy?
Based on animal studies, Lupron Depot-Ped may cause fetal harm when administered to a pregnant woman. Talk to your doctor if you are already pregnant or if you have plans on becoming pregnant. They will recommend what is best for you.













