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Loestrin FE is the brand name for norethindrone acetate, ethinyl estradiol, and ferrous fumarate. It is available as an oral tablet.

Loestrin FE is available as a combination norethindone acetate/ethinyl estradiol tablet that contains 1 mg/20 mcg plus 75 mg of ferrous fumarate and 1.5 mg/30 mcg plus 75 mg of ferrous fumarate.

Loestrin FE is a combination oral contraceptive (COC) that is used to prevent pregnancy in women.

Loestrin FE is a combination of 2 hormones, ethinyl estradiol (an estrogen) and norethindrone acetate (a progestin) that work together to prevent pregnancy. It does this by preventing ovulation (release of an egg from the ovary), changing cervical mucus to block sperm from entering the uterus, and changing the lining of the the uterus so the fertilized egg cannot attach to the uterine wall.

Loestrin FE is typically taken by mouth once a day. The first 21 to 24 days contain active ingredients while the last 7 contain ferrous fumarate.

Loestrin FE is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. You should not take this medication if you have any of the following:

• Thrombophlebitis or thromboembolic disorders
• A past history of deep vein thrombophlebitis or thromboembolic disorders
• Cerebral vascular or coronary artery disease
• Current diagnosis of, or history of, breast cancer, which may be hormone sensitive
• Carcinoma of the endometrium or other known or suspected estrogen-dependent neoplasia
• Undiagnosed abnormal genital bleeding
• Cholestatic jaundice of pregnancy or jaundice with prior pill use
• Hepatic adenomas or carcinomas

Common side effects of Loestrin FE include:

• Nausea
• Vomiting
• Stomach cramps and bloating
• Bleeding between periods
• Spotting
• Change in the flow of period
• Missing periods
• Swelling
• Breast changes
• Weight changes
• Mental depression
• Vaginal yeast infection

Serious side effects are rare with JUNEL FE. Contact your healthcare provider immediately if you experience any of the following.

• Heart attack: chest pain, stomach discomfort, sweating, nausea, dizziness
• Stroke: sudden numbness or weakness in the arm, leg, or face, confusion, trouble seeing, headache, difficulty walking
• Deep vein thrombosis (blood clot in the leg): leg cramp, swelling, pain, muscle tightness
• Pulmonary embolism (blood clot in the lung): cough, chest pain, trouble breathing, racing heart

The following medications may interact with JUNEL FE: HCV drug combinations containing ombitasvir/paritaprevir/ritonavir, with or without dasabuvir – May cause ALT elevations. Antibiotics, anticonvulsants, and other drugs that increase the metabolism of contraceptive steriods, including rifampin, rifabutin, barbiturates, primidone, phenylbutazone, phenytoin, dexamethasone, carbamazepine, felbamate, oxcarbazepine, topiramate, griseofulvin, and modafinil: Effectiveness of JUNEL FE may be reduced.

Teva Pharmaceuticals

JUNEL FE is contraindicated during pregnancy as it may cause fetal harm when administered to pregnant women.

• Norethindrone