Key facts about Leqvio
What is Leqvio?
Leqvio is the brand name for inclisiran and is available as a subcutaneous injection.
What dosages is Leqvio available in?
Leqvio is available as a 284 mg/1.5 mL (189 mg/mL) in a single-dose prefilled syringe.
What is Leqvio used for?
Leqvio is a siRNA and is used to treat high cholesterol, including heterozygous familial hypercholesterolemia (HeFH), in adults; as add-on to heart-healthy diet and statin therapy.
How does Leqvio work?
Leqvio is a small interfering RNA (siRNA) medication. It gets absorbed into your liver and breaks down the gene that makes a protein called PCSK9. Normally, PCSK9 helps adjust the amount of cholesterol in your body. By stopping your liver from making PCSK9, Leqvio helps your liver remove “bad” cholesterol (LDL, or low-density lipoprotein) from your body.
How do I take Leqvio?
The typical dose of Leqvio is 284 mg injected under the skin every 3 months for 2 doses, then given every 6 months thereafter.
Is it safe for me to take Leqvio?
Leqvio is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you.
Leqvio Common Side Effects
Common side effects of Leqvio:
- Injection site reaction
Leqvio Serious Side Effects
Serious side effects are rare with Leqvio.
Effects of other drugs, drug classes and over-the-counter products on Leqvio
There are no major drug interactions listed for Leqvio. However, always let your physician and pharmacist know about any other medications or supplements (including prescribed and over-the-counter medications, vitamins, and dietary or herbal supplements) that you are currently taking.
Who makes Leqvio?
Novartis Pharmaceuticals
Is Leqvio safe in pregnancy?
Discontinue Leqvio when pregnancy is recognized.
