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MEDICAL INFORMATION
Inclisiran Key Facts
What dosages is Inclisiran available in?
Inclisiran is available as a 284 mg/1.5 mL (189 mg/mL) in a single-dose prefilled syringe.
What is Inclisiran used for?
Inclisiran is a siRNA and is used to treat high cholesterol, including heterozygous familial hypercholesterolemia (HeFH), in adults; as add-on to heart-healthy diet and statin therapy.
How does Inclisiran work?
Inclisiran is a small interfering RNA (siRNA) medication. It gets absorbed into your liver and breaks down the gene that makes a protein called PCSK9. Normally, PCSK9 helps adjust the amount of cholesterol in your body. By stopping your liver from making PCSK9, Inclisiran helps your liver remove “bad” cholesterol (LDL, or low-density lipoprotein) from your body.
How do I take Inclisiran?
The typical dose of Inclisiran is 284 mg injected under the skin every 3 months for 2 doses, then given every 6 months thereafter.
Is it safe for me to take Inclisiran?
Inclisiran is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you.
Inclisiran Common Side Effects
Common side effects of Inclisiran:
- Injection site reaction
Inclisiran Serious Side Effects
Serious side effects are rare with Inclisiran.
Effects of other drugs, drug classes and over-the-counter products on Inclisiran
There are no major drug interactions listed for Inclisiran. However, always let your physician and pharmacist know about any other medications or supplements (including prescribed and over-the-counter medications, vitamins, and dietary or herbal supplements) that you are currently taking.
Who makes Inclisiran?
Various FDA-approved generic manufacturers
Is Inclisiran safe in pregnancy?
Discontinue Inclisiran when pregnancy is recognized.
What is the brand name for Inclisiran?
Medical Disclaimer
NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.
The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.
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