Key facts about Lenvima
What is Lenvima?
Lenvima is the brand name for lenvatinib and is available as an oral capsule.
What dosages is Lenvima available in?
Lenvima is available as a 4 mg and 10 mg oral capsule.
What is Lenvima used for?
Lenvima is a kinase inhibitor that is indicated for:
- Differentiated thyroid cancer (DTC
- Renal cell carcinoma (RCC)
- Hepatocellular carcinoma (HCC)
- Endometrial carcinoma (EC)
How does Lenvima work?
Lenvima is a targeted cancer therapy classified as a multiple receptor tyrosine kinase inhibitor (TKI). It is not a traditional chemotherapy drug. It works by blocking specific proteins (kinases) inside the cancer cells and their surrounding environment to stop tumor growth and survival.
How do I take Lenvima?
Lenvima is typically taken once a day. It can be used by itself or along with pembrolizumab or everolimus, depending on what is being treated.
Is it safe for me to take Lenvima?
Lenvima is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you.
Lenvima Common Side Effects
Common side effects of Lenvima:
- Fatigue or unusual tiredness
- Weight loss
- Joint and muscle pain
- Headache
- Hoarseness or voice changes
- Diarrhea
- Nausea and vomiting
- Decreased appetite
- Stomach pain
- Mouth sores or inflammation
- Constipation
- Rash
- Swelling
Lenvima Serious Side Effects
Serious side effects are rare with Lenvima. Contact your healthcare provider immediately if you experience any of the following:
- Allergic reactions
- Bleeding
- Heart attack or stroke
- Heart failure
- Heart rhythm changes
- High or low thyroid levels
- Kidney injury
- Liver injury
- Low calcium level
- Osteonecrosis of the jaw
- Posterior reversible encephalopathy syndrome (PRES)
Effects of other drugs, drug classes and over-the-counter products on Lenvima
The following medications may interact with Lenvima:
- Drugs that prolong the QT interval
Who makes Lenvima?
Eisai Inc.
Is Lenvima safe in pregnancy?
Lenvima can harm your unborn baby. Females who are able to become pregnant should do a pregnancy test before starting treatment. They should use an effective method of birth control (contraception) during treatment and for 30 days after the last dose. Tell your healthcare provider right away if you become pregnant or think you are pregnant during treatment.













