Key facts about Lenvatinib
What dosages is Lenvatinib available in?
Lenvatinib is available as a 4 mg and 10 mg oral capsule.
What is Lenvatinib used for?
Lenvatinib is a kinase inhibitor that is indicated for:
- Differentiated thyroid cancer (DTC
- Renal cell carcinoma (RCC)
- Hepatocellular carcinoma (HCC)
- Endometrial carcinoma (EC)
How does Lenvatinib work?
Lenvatinib is a targeted cancer therapy classified as a multiple receptor tyrosine kinase inhibitor (TKI). It is not a traditional chemotherapy drug. It works by blocking specific proteins (kinases) inside the cancer cells and their surrounding environment to stop tumor growth and survival.
How do I take Lenvatinib?
Lenvatinib is typically taken once a day. It can be used by itself or along with pembrolizumab or everolimus, depending on what is being treated.
Is it safe for me to take Lenvatinib?
Lenvatinib is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you.
Lenvatinib Common Side Effects
Common side effects of Lenvatinib:
- Fatigue or unusual tiredness
- Weight loss
- Joint and muscle pain
- Headache
- Hoarseness or voice changes
- Diarrhea
- Nausea and vomiting
- Decreased appetite
- Stomach pain
- Mouth sores or inflammation
- Constipation
- Rash
- Swelling
Lenvatinib Serious Side Effects
Serious side effects are rare with Lenvatinib. Contact your healthcare provider immediately if you experience any of the following:
- Allergic reactions
- Bleeding
- Heart attack or stroke
- Heart failure
- Heart rhythm changes
- High or low thyroid levels
- Kidney injury
- Liver injury
- Low calcium level
- Osteonecrosis of the jaw
- Posterior reversible encephalopathy syndrome (PRES)
Effects of other drugs, drug classes and over-the-counter products on Lenvatinib
The following medications may interact with Lenvatinib:
- Drugs that prolong the QT interval
Who makes Lenvatinib?
Various FDA-approved generic manufacturers
Is Lenvatinib safe in pregnancy?
Lenvatinib can harm your unborn baby. Females who are able to become pregnant should do a pregnancy test before starting treatment. They should use an effective method of birth control (contraception) during treatment and for 30 days after the last dose. Tell your healthcare provider right away if you become pregnant or think you are pregnant during treatment.
