Key facts about High Molecular Weight Hyaluronan
What dosages is High Molecular Weight Hyaluronan available in?
High Molecular Weight Hyaluronan is available as a pre-filled syringe that contains:
- Sodium Hyaluronate 88 mg (nominal)
- Sodium Chloride 36 mg
- Potassium Chloride 0.8 mg
- Sodium Phosphate, Dibasic 4.6 mg
- Potassium Phosphate, Monobasic 0.8 mg
What is High Molecular Weight Hyaluronan used for?
High Molecular Weight Hyaluronan is a viscoelastic and is used to treat pain due to osteoarthritis of the knee.
How does High Molecular Weight Hyaluronan work?
High Molecular Weight Hyaluronan is a viscoelastic. It’s similar to a substance that’s naturally found in the connective tissues in your body. When it’s injected into the knee, it helps lubricate your knee joint so that you can move it smoothly. This can reduce pain from osteoarthritis in your knee.
How do I take High Molecular Weight Hyaluronan?
There are many injectable injectable hyaluronic acid products available. Your provider will ensure you’re getting your injections at the right dose and at the right time, depending on your product. In general, this medication is injected intraarticularly into your knee once weekly for 1 to 5 weeks.
Is it safe for me to take High Molecular Weight Hyaluronan?
High Molecular Weight Hyaluronan is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you.
- Do not administer to patients with known hypersensitivity (allergy) to hyaluronate preparations.
- Do not administer to patients with known hypersensitivity (allergy) to gram positive bacterial proteins
- Do not inject High Molecular Weight Hyaluronan in the knees of patients with infections or skin diseases in the area of the injection site or joint
- Do not administer to patients with known systemic bleeding disorders
High Molecular Weight Hyaluronan Common Side Effects
Common side effects of High Molecular Weight Hyaluronan:
- Joint pain and swelling
- Back pain
- Muscle and bone pain
- Injection site reaction (redness, swelling)
High Molecular Weight Hyaluronan Serious Side Effects
Serious side effects are rare with High Molecular Weight Hyaluronan. Contact your healthcare provider immediately if you experience any of the following.
- Severe allergic reaction: rash, trouble breathing, swelling of lips, tongue, or throat
Effects of other drugs, drug classes and over-the-counter products on High Molecular Weight Hyaluronan
There are no major drug interactions listed for High Molecular Weight Hyaluronan. However, always let your physician and pharmacist know about any other medications or supplements (including prescribed and over-the-counter medications, vitamins, and dietary or herbal supplements) that you are currently taking.
Who makes High Molecular Weight Hyaluronan?
Various FDA-approved generic manufacturers
Is High Molecular Weight Hyaluronan safe in pregnancy?
The safety and effectiveness of the use of High Molecular Weight Hyaluronan in pregnant women has not been tested. It should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.













