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MEDICAL INFORMATION
Galcanezumab-GNLM Key Facts
What dosages is Galcanezumab-GNLM available in?
Galcanezumab-GNLM is available as one of the following subcutaneous injections:
- 120 mg/mL solution in a single-dose prefilled pen
- 120 mg/mL solution in a single-dose prefilled syringe
- 100 mg/mL solution in a single-dose prefilled syringe
What is Galcanezumab-GNLM used for?
Galcanezumab-GNLM is a monoclonal antibody and is used for the following:
- Migraine prevention
- Episodic (occasional) cluster headaches
How does Galcanezumab-GNLM work?
Galcanezumab-GNLM is a monoclonal antibody. It blocks a protein in your body called calcitonin gene-related peptide (CGRP) ligand. Your nerves release CGRPs during migraine attacks and cluster headaches. CGRPs cause the blood vessels in your brain to swell, which can lead to pain. When Galcanezumab-GNLM blocks these proteins, it can prevent migraines and ease pain from cluster headaches.
How do I take Galcanezumab-GNLM?
Galcanezumab-GNLM is dosed as following:
- Migraine prevention: The typical dose is 240 mg (two injections of 120 mg each, one right after the other) injected under the skin once when you first start the medication. Then, inject 120 mg under the skin once a month
- Episodic cluster headaches: The typical dose is 300 mg (three injections of 100 mg each, one right after the other) injected under the skin once at the start of your cluster period. Then, inject 300 mg under the skin once a month, until the end of your cluster period
Is it safe for me to take Galcanezumab-GNLM?
Galcanezumab-GNLM is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you.
Galcanezumab-GNLM Common Side Effects
Common side effects of Galcanezumab-GNLM:
- Pain, itching, warmth, and other injection site reactions
- Sore throat, runny nose
- Back pain
Galcanezumab-GNLM Serious Side Effects
Serious side effects are rare with Galcanezumab-GNLM. Contact your healthcare provider immediately if you experience any of the following.
- Serious allergic reactions: hives, swelling in the face and eyes, swollen throat, trouble breathing, wheezing, nausea, vomiting, diarrhea, dizziness, fainting
Effects of other drugs, drug classes and over-the-counter products on Galcanezumab-GNLM
There are no major drug interactions listed for Galcanezumab-GNLM. However, always let your physician and pharmacist know about any other medications or supplements (including prescribed and over-the-counter medications, vitamins, and dietary or herbal supplements) that you are currently taking.
Who makes Galcanezumab-GNLM?
Various FDA-approved generic manufacturers
Is Galcanezumab-GNLM safe in pregnancy?
There are no adequate data on the developmental risk associated with the use of Galcanezumab-GNLM in pregnant women. It should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. There is a pregnancy exposure registry that monitors pregnancy outcomes in women exposed to Galcanezumab-GNLM during pregnancy. Healthcare providers are encouraged to register pregnant patients, or pregnant women may enroll themselves in the registry by calling 1-833-464-4724 or by contacting the company at Migraine pregnancy registry
What is the brand name for Galcanezumab-GNLM?
Medical Disclaimer
NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.
The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.
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