Key facts about Fruqintinib
What dosages is Fruqintinib available in?
Fruqintinib is available as 1 mg and 5 mg oral capsule.
What is Fruqintinib used for?
Fruqintinib is a kinase inhibitor indicated for the treatment of adult patients with metastatic colorectal cancer (mCRC) who have been previously treated with fluoropyrimidine-, oxaliplatin-, and irinotecan-based chemotherapy, an anti-VEGF therapy, and, if RAS wild-type and medically appropriate, an anti-EGFR therapy.
How does Fruqintinib work?
Fruqintinib works by blocking a protein that causes cancer cells to grow and multiply. This helps to slow or stop the spread of cancer cells.
How do I take Fruqintinib?
The recommended dose of Fruqintinib is 5 mg orally once daily, with or without food for the first 21 days of each 28-day cycle
Is it safe for me to take Fruqintinib?
Fruqintinib is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you.
Fruqintinib Common Side Effects
Common side effects of Fruqintinib:
- Hypertension
- Palmar-plantar erythrodysesthesia (a skin reaction that affects the palms of your hands and the soles of your feet)
- Abdominal pain
- Diarrhea
Fruqintinib Serious Side Effects
Serious side effects are rare with Fruqintinib. Contact your doctor if you experience any of the following.
- Severe bleeding (hemorrhage).
- Infections
- A tear in your stomach or intestinal wall (gastrointestinal perforation)
- Liver problems
- Posterior Reversible Encephalopathy Syndrome (PRES)
- Wound healing problems
- Blood clots in your blood vessels (arteries)
Effects of other drugs, drug classes and over-the-counter products on Fruqintinib
The following medications may interact with Fruqintinib:
- Strong or Moderate CYP3A Inducers: Avoid concomitant use
Who makes Fruqintinib?
Various FDA-approved generic manufacturers
Is Fruqintinib safe in pregnancy?
Fruqintinib can harm your unborn baby. You should not become pregnant during treatment with Fruqintinib. If you can become pregnant, your healthcare provider will do a pregnancy test before you start treatment with Fruqintinib. Use effective birth control (contraception) during treatment and for 2 weeks after your last dose of Fruqintinib. Tell your healthcare provider right away if you become pregnant during treatment with Fruqintinib. Males with female partners who can become pregnant should use effective birth control during treatment and for 2 weeks after your last dose of Fruqintinib. Tell your healthcare provider right away if your partner becomes pregnant during your treatment with Fruqintinib.
