FIRAZYR
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Manufactured by Shire US Inc.
*You can pay as little as $0 per fill using Drug Coupons or Patient Assistance Programs. Subject to applicability & eligibility requirements.
This content is intended for US audiences only
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FIRAZYR Uses, Side Effects, Interactions, Warnings & Dosing
What is FIRAZYR?
FIRAZYR is the brand name for icatibant and is available as a subcutaneous injection.
What dosages is FIRAZYR available in?
FIRAZYR is available as a 10 mg/ml subcutaneous injection.
What is FIRAZYR used for?
FIRAZYR is a bradykinin B2 receptor antagonist and is used to treat treatment of sudden attacks of hereditary angioedema (HAE).
How does FIRAZYR work?
FIRAZYR is a bradykinin B2 receptor antagonist. It works by blocking the activity of a natural substance in the body called bradykinin. Bradykinin causes blood vessels to dilate (widen) and lead to swelling. In HAE, there’s too much bradykinin produced in your body, which causes severe swelling in different parts of your body (hands, feet, stomach, face, throat). By blocking bradykinin, FIRAZYR can help lower pain and swelling from an HAE attack.
How do I take FIRAZYR?
FIRAZYR is typically started at 30 mg injected under the skin (subcutaneous) in the stomach area. If needed, additional doses can be given at least 6 hours apart, with a maximum of 3 doses in 24 hours.
Is it safe for me to take FIRAZYR?
FIRAZYR is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you.
FIRAZYR Common Side Effects
Common side effects of FIRAZYR:
- Injection site reaction
- Fever
- Abnormal liver labs
- Dizziness
- Rash
FIRAZYR Serious Side Effects
Serious side effects are rare with FIRAZYR.
Effects of other drugs, drug classes and over-the-counter products on FIRAZYR
The following medications may interact with FIRAZYR:
- FIRAZYR is a bradykinin B2 receptor antagonist and thereby has the potential to have a pharmacodynamic interaction with ACE inhibitors where FIRAZYR may attenuate the antihypertensive effect of ACE inhibitors. Clinical trials to date have excluded subjects taking ACE inhibitors
Who makes FIRAZYR?
Shire US Inc.
Is FIRAZYR safe in pregnancy?
It is not known if FIRAZYR will harm your unborn baby.
You and your healthcare provider will decide if FIRAZYR is right for you.
The FDA's medical product safety reporting program for health professionals, patients and consumers.
Learn more about reporting side effects
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Medical Disclaimer
NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.
The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.
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