icatibant
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Manufactured by various FDA-approved generic manufacturers.
*You can pay as little as $0 per fill using Drug Coupons or Patient Assistance Programs. Subject to applicability & eligibility requirements.
This content is intended for US audiences only
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icatibant Uses, Side Effects, Interactions, Warnings & Dosing
What dosages is icatibant available in?
icatibant is available as a 10 mg/ml subcutaneous injection.
What is icatibant used for?
icatibant is a bradykinin B2 receptor antagonist and is used to treat treatment of sudden attacks of hereditary angioedema (HAE).
How does icatibant work?
icatibant is a bradykinin B2 receptor antagonist. It works by blocking the activity of a natural substance in the body called bradykinin. Bradykinin causes blood vessels to dilate (widen) and lead to swelling. In HAE, there’s too much bradykinin produced in your body, which causes severe swelling in different parts of your body (hands, feet, stomach, face, throat). By blocking bradykinin, icatibant can help lower pain and swelling from an HAE attack.
How do I take icatibant?
icatibant is typically started at 30 mg injected under the skin (subcutaneous) in the stomach area. If needed, additional doses can be given at least 6 hours apart, with a maximum of 3 doses in 24 hours.
Is it safe for me to take icatibant?
icatibant is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you.
icatibant Common Side Effects
Common side effects of icatibant:
- Injection site reaction
- Fever
- Abnormal liver labs
- Dizziness
- Rash
icatibant Serious Side Effects
Serious side effects are rare with icatibant.
Effects of other drugs, drug classes and over-the-counter products on icatibant
The following medications may interact with icatibant:
- icatibant is a bradykinin B2 receptor antagonist and thereby has the potential to have a pharmacodynamic interaction with ACE inhibitors where icatibant may attenuate the antihypertensive effect of ACE inhibitors. Clinical trials to date have excluded subjects taking ACE inhibitors
Who makes icatibant?
Various FDA-approved generic manufacturers
Is icatibant safe in pregnancy?
It is not known if icatibant will harm your unborn baby.
You and your healthcare provider will decide if icatibant is right for you.
The FDA's medical product safety reporting program for health professionals, patients and consumers.
Learn more about reporting side effects
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Medical Disclaimer
NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.
The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.
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