ESBRIET

View ESBRIET savings options available to you including Manufacturer Coupons, Rx Advantage Savings Card, Canadian Prescription Savings or ESBRIET Patient Assistance Program.

Programs are suitable for individuals who want to buy ESBRIET without insurance, with insurance or for those who are underinsured. You can pay as little as $0 per fill.*

Manufactured by Genentech, Inc.

*Applicable to Drug Coupons & Patient Assistance Programs

This content is intended for US audiences only

Drug savings programs

  • Qualified

    Rx Advantage Card

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    Save up to 90%

  • Available

    Canadian Prescription Savings

    N/A
    Manufactured by
    N/A
    Powered by
    Prescription Help Logo
  • Unavailable

    Drug Coupons

    A hand holds a Copay Savings Card that states eligible patients with commercial insurance may pay as little as $0 per tube for Opzelura.
    Unavailable
  • Available

    Patient Assistance Programs

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    FREE

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Jamie Winn NowPatientGreen tick
Updated on 26 Apr 2024

Learn more about ESBRIET

What is ESBRIET?

What is ESBRIET?

ESBRIET is the brand name for pirfenidone oral capsules.

What dosages is ESBRIET available in?

What dosages is ESBRIET available in?

ESBRIET is available as a 267 mg oral capsule.

What is ESBRIET used for?

What is ESBRIET used for?

ESBRIET is an antifibrotic agent that is used to treat idiopathic pulmonary fibrosis (IPF).

How does ESBRIET work?

How does ESBRIET work?

It is not exactly clear how ESBRIET works, but it lessens the chemicals that cause inflammation and fibrosis (scarring) in the lungs. As a result, your lungs don’t scar as quickly and your breathing doesn’t worsen as much over time.

How do I take ESBRIET?

How do I take ESBRIET?

When first starting ESBRIET, you’ll need to follow a specific dose schedule.

  • Week 1: Take 267 mg (1 pill) by mouth three times daily
  • Week 2: Take 534 mg (2 pills) by mouth three times daily
  • Week 3 and beyond: Take 801 (3 pills) by mouth three times daily. ESBRIET is also available as a 801 mg tablet, so you may eventually get to switch to 1 pill a day once you reach this maintenance dose
Is it safe for me to take ESBRIET?

Is it safe for me to take ESBRIET?

ESBRIET is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you.

ESBRIET Common Side Effects

ESBRIET Common Side Effects

Common side effects of ESBRIET:

  • Nausea
  • Rash
  • Stomach pain or discomfort
  • Common cold symptoms
  • Diarrhea
  • Tiredness
  • Headache
  • Indigestion
  • Dizziness
  • Vomiting
  • Poor appetite
ESBRIET Serious Side Effects

ESBRIET Serious Side Effects

Serious side effects are rare with ESBRIET. Contact your healthcare provider immediately if you experience any of the following.

  • Liver injury: yellowing of the skin or eyes, dark-colored urine, pain on the right side of your torso, more bleeding or bruising, tiredness that doesn’t go away
    Severe sunburn or rash
Effects of other drugs, drug classes and over-the-counter products on ESBRIET

Effects of other drugs, drug classes and over-the-counter products on ESBRIET

The following medications may interact with ESBRIET:

  • Moderate (e.g., ciprofloxacin) and strong inhibitors of CYP1A2 (e.g. fluvoxamine) increase systemic exposure of ESBRIET and may alter the adverse reaction profile of ESBRIET. Discontinue fluvoxamine prior to administration of ESBRIET or reduce to one capsule three times a day
  • Consider dosage reduction with use of ciprofloxacin
Who makes ESBRIET?

Who makes ESBRIET?

Genentech, Inc.

Is ESBRIET safe in pregnancy?

Is ESBRIET safe in pregnancy?

It is not known if ESBRIET will harm your unborn baby. Tell your healthcare provider if you are pregnant or plan to become pregnant while using ESBRIET.

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What to do if you missed your ESBRIET dose

The FDA's medical product safety reporting program for health professionals, patients and consumers.

Learn more about reporting side effects
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Drug Savings Tips

Medical Disclaimer

NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.

The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.

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