ESBRIET
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Manufactured by Genentech, Inc.
*You can pay as little as $0 per fill using Drug Coupons or Patient Assistance Programs. Subject to applicability & eligibility requirements.
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ESBRIET Uses, Side Effects, Interactions, Warnings & Dosing
What is ESBRIET?
ESBRIET is the brand name for pirfenidone oral capsules.
What dosages is ESBRIET available in?
ESBRIET is available as a 267 mg oral capsule.
What is ESBRIET used for?
ESBRIET is an antifibrotic agent that is used to treat idiopathic pulmonary fibrosis (IPF).
How does ESBRIET work?
It is not exactly clear how ESBRIET works, but it lessens the chemicals that cause inflammation and fibrosis (scarring) in the lungs. As a result, your lungs don’t scar as quickly and your breathing doesn’t worsen as much over time.
How do I take ESBRIET?
When first starting ESBRIET, you’ll need to follow a specific dose schedule.
- Week 1: Take 267 mg (1 pill) by mouth three times daily
- Week 2: Take 534 mg (2 pills) by mouth three times daily
- Week 3 and beyond: Take 801 (3 pills) by mouth three times daily. ESBRIET is also available as a 801 mg tablet, so you may eventually get to switch to 1 pill a day once you reach this maintenance dose
Is it safe for me to take ESBRIET?
ESBRIET is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you.
ESBRIET Common Side Effects
Common side effects of ESBRIET:
- Nausea
- Rash
- Stomach pain or discomfort
- Common cold symptoms
- Diarrhea
- Tiredness
- Headache
- Indigestion
- Dizziness
- Vomiting
- Poor appetite
ESBRIET Serious Side Effects
Serious side effects are rare with ESBRIET. Contact your healthcare provider immediately if you experience any of the following.
- Liver injury: yellowing of the skin or eyes, dark-colored urine, pain on the right side of your torso, more bleeding or bruising, tiredness that doesn’t go away
Severe sunburn or rash
Effects of other drugs, drug classes and over-the-counter products on ESBRIET
The following medications may interact with ESBRIET:
- Moderate (e.g., ciprofloxacin) and strong inhibitors of CYP1A2 (e.g. fluvoxamine) increase systemic exposure of ESBRIET and may alter the adverse reaction profile of ESBRIET. Discontinue fluvoxamine prior to administration of ESBRIET or reduce to one capsule three times a day
- Consider dosage reduction with use of ciprofloxacin
Who makes ESBRIET?
Genentech, Inc.
Is ESBRIET safe in pregnancy?
It is not known if ESBRIET will harm your unborn baby. Tell your healthcare provider if you are pregnant or plan to become pregnant while using ESBRIET.
What to do if you missed your ESBRIET dose
The FDA's medical product safety reporting program for health professionals, patients and consumers.
Learn more about reporting side effectsDrug Savings Tips
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Are the NowPatient ESBRIET savings programs suitable for everyone, regardless of insurance status?
Are the NowPatient drug savings programs suitable for brand and generic versions of ESBRIET?
If you have Medicare Part D or Medicare Advantage and none of the ESBRIET savings options are applicable or affordable for me, what can you do?
I am uninsured or underinsured and none of the ESBRIET prescription saving options are applicable or affordable for me, what can I do?
I am commercially or privately insured and none of the ESBRIET prescription saving options are applicable or affordable for me, what can I do?
If I have federal, state or commercial insurance and none of the ESBRIET prescription saving options are applicable or affordable for me, are there any other support organisations that can help me with my co-insurance or copay?
Medical Disclaimer
NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.
The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.
Things to know
What is the success rate of Esbriet?
Can you live 20 years with pulmonary fibrosis?
Can you live more than 10 years with pulmonary fibrosis?
How long does it take for Esbriet to work?
What is the life expectancy of a person with pulmonary fibrosis?
Does pulmonary fibrosis ever stop progressing?
What is the difference between OFEV and Esbriet?
What does Esbriet do for the lungs?
What is the longest life expectancy of pulmonary fibrosis?
Does pulmonary fibrosis ever get better?
Is Esbriet expensive?
What is end of life care for pulmonary fibrosis?
Does pulmonary fibrosis shorten life expectancy?
What are the side effects of the drug Esbriet?
What is the new treatment for interstitial lung disease?
Why does pulmonary fibrosis get worse?
Is Esbriet being discontinued?
What is the new drug for interstitial lung disease?
Are we close to a cure for pulmonary fibrosis?
What is the new wonder drug for cystic fibrosis?
What is the new miracle drug for CF?
Does pulmonary fibrosis ever go into remission?
Is there a generic drug for Esbriet?
What is the recent treatment for lung fibrosis?
What is the current treatment for idiopathic pulmonary fibrosis?
What drugs are used to reverse pulmonary fibrosis?
What are the side effects of Esbriet?
What is the price of Esbriet?
Why is Esbriet so expensive?
Is generic Esbriet available?
What is the best drug for fibrosis in the lungs?
What is the difference between Ofev and Esbriet?
Is pirfenidone covered by Medicare?
What foods should you avoid while taking pirfenidone?
What new drug reverses pulmonary fibrosis?
How much does it cost to treat pulmonary fibrosis?
What is the generic name for Esbriet?
How much is generic pirfenidone?
Why is Ofev so expensive?
Can you take prednisone and Esbriet together?
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