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MEDICAL INFORMATION
Eplontersen Key Facts
What dosages is Eplontersen available in?
Eplontersen is an oral capsule that contains 150 mg of oteseconazole.
What is Eplontersen used for?
Eplontersen is an antifungal medication used to treat recurrent vulvovaginal candidiasis (chronic vaginal yeast infection) in people who can’t get pregnant.
How does Eplontersen work?
Eplontersen is an azole antifungal medication that kills the fungus that causes yeast infections. It does so by blocking the fungus from making an important substance needed for its outer protective layer. It also kills the fungus by causing a toxic substance to build up inside of it.
How do I take Eplontersen?
Eplontersen is either taken by itself or after taking Diflucan (fluconazole).
Eplontersen (oteseconazole) only – dosing lasts a total of 12 weeks
Day 1:
- Take 600 mg (4 capsules) by mouth once.
- Day 2: Take 450 mg (3 capsules) by mouth once.
- Starting on Day 14: Take 150 mg (1 capsule) by mouth once a week for 11 weeks.
- Eplontersen and Diflucan: – dosing lasts a total of 14 weeks
- Day 1: Take 150 mg of Diflucan.
- Day 4: Take 150 mg of Diflucan.
- Day 7: Take 150 mg of Diflucan.
- Days 14 through 20: Take 150 mg (1 capsule) of Eplontersen by mouth once a day.
- Starting on Day 28: Take 150 mg (1 capsule) of Eplontersen by mouth once a week for 11 weeks.
Is it safe for me to take Eplontersen?
Eplontersen is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. You should not use this medication in the following:
- Females that can get pregnant or who already are pregnant
- Lactating women
- Hypersensitivity to oteseconazole
Eplontersen Common Side Effects
Common side effects of Eplontersen:
- Headache
- Nausea
Eplontersen Serious Side Effects
Serious side effects are rare with Eplontersen. Contact your healthcare provider immediately if you experience any of the following:
- Allergic reaction
Effects of other drugs, drug classes and over-the-counter products on Eplontersen
The following medications may interact with Eplontersen:
- BCRP (Breast Cancer Resistance Protein) substrates
Who makes Eplontersen?
Various FDA-approved generic manufacturers
Is Eplontersen safe in pregnancy?
People who are of reproductive potential (able to get pregnant), pregnant, or breastfeeding shouldn’t take Eplontersen because of the risks to unborn babies and breastfed infants.
Medical Disclaimer
NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.
The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.
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