Key facts about Epkinly
What is Epkinly?
Epkinly is the brand name for epcoritamab-bysp and is available as a subcutaneous injection.
What dosages is Epkinly available in?
Epkinly is available as a 4 mg/0.8 mL and 48 mg/0.8 mL single-dose vial.
What is Epkinly used for?
Epkinly is a type of monoclonal antibody used to treat certain lymphoma.
How does Epkinly work?
Epkinly is is a bispecific CD20-directed CD3 T-cell engager. It works by helping your immune system slow or stop the spread of cancer cells.
How do I take Epkinly?
Epkinly is administered as a subcutaneous injection in a specific, multi-phase, 28-day cycle “step-up” dosing schedule to minimize the risk of cytokine release syndrome (CRS). The exact schedule and initial doses may vary slightly depending on what is being treated.
Is it safe for me to take Epkinly?
Epkinly is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you.
Epkinly Common Side Effects
Common side effects of Epkinly:
- Fatigue
- Muscle and bone pain
- Injection site reactions
- Fever
- Nausea
- Diarrhea
- Upper respiratory infection, such as sinusitis
- COVID-19
- Skin rash
- Cough
- Headache
Epkinly Serious Side Effects
Serious side effects are rare with Epkinly. Contact your healthcare provider immediately if you experience any of the following:
- Low level of platelets
- Low level of white blood cells
- Low level of red blood cells
- Serious and life threatening infections, including
- Pneumonia, COVID-19, urinary tract infection (UTI), and sepsis
- Increased risk of cytokine release syndrome
Effects of other drugs, drug classes and over-the-counter products on Epkinly
The following medications may interact with Epkinly:
- Certain CYP substrates
Who makes Epkinly?
AbbVie Inc.
Is Epkinly safe in pregnancy?
Based on the mechanism of action, Epkinly may cause fetal harm when administered to a pregnant woman. Talk to your doctor if you are already pregnant or if you have plans on becoming pregnant. They will recommend what is best for you.
