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MEDICAL INFORMATION
Enasidenib Key Facts
What dosages is Enasidenib available in?
Enasidenib is available as a 50 mg and 100 mg oral tablet.
What is Enasidenib used for?
Enasidenib is an IDH2 inhibitor that is used to treat adults with relapsed or refractory acute myeloid leukemia (AML) with changes in the IDH2 gene.
How does Enasidenib work?
Enasidenib is an IDH2 inhibitor. When Enasidenib blocks IDH2, it lowers the number of cancer cells and allows the young blood cells to mature into healthy cells.
How do I take Enasidenib?
Enasidenib is typically dosed as 100 mg by mouth once daily.
Is it safe for me to take Enasidenib?
Enasidenib is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you.
Enasidenib Common Side Effects
Common side effects of Enasidenib:
- Higher bilirubin
- Lower calcium levels
- Nausea
- Diarrhea
- Lower potassium levels
- Vomiting
- Lower appetite
- Lower phosphorus levels
- Differentiation syndrome
- Higher white blood cell counts
- Taste changes
Enasidenib Serious Side Effects
Serious side effects are rare with Enasidenib. Contact your healthcare provider immediately if you experience any of the following.
- Differentiation syndrome: fever, sudden weight gain, trouble breathing, chest pain, swelling in legs
Effects of other drugs, drug classes and over-the-counter products on Enasidenib
There are no major drug interactions listed for Enasidenib. However, always let your physician and pharmacist know about any other medications or supplements (including prescribed and over-the-counter medications, vitamins, and dietary or herbal supplements) that you are currently taking.
Who makes Enasidenib?
Various FDA-approved generic manufacturers
Is Enasidenib safe in pregnancy?
Enasidenib can cause harm to your unborn baby if taken during pregnancy. If you are able to become pregnant, your healthcare provider will do a pregnancy test before you start taking Enasidenib. Females who are able to become pregnant and who take Enasidenib should use effective birth control (contraception) during treatment with Enasidenib and for at least 1 month after your last dose of Enasidenib. Males who have female partners that are able to become pregnant should use effective birth control during treatment with Enasidenib and for at least 1 month after your last dose of Enasidenib. Enasidenib may affect how hormonal contraceptives work and may cause them to not work as well. Talk to your healthcare provider about birth control methods that may be right for you while taking Enasidenib.
What is the brand name for Enasidenib?
Medical Disclaimer
NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.
The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.
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