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MEDICAL INFORMATION
Efudex Key Facts
What is Efudex?
Efudex is the brand name for fluorouracil and is available as a topical solution and cream.
What dosages is Efudex available in?
Efudex is available as a 2% and 5% topical solution and a 5% topical cream.
What is Efudex used for?
Efudex is an antimetabolite and is used for the following:
Actinic (or solar) keratosis (scaly pre-cancerous spot or growth on the skin) in adults Basal cell carcinoma (certain type of skin cancer) in adults
How does Efudex work?
Efudex is an antimetabolite. It works by getting in the way of cells making copies of their genetic material. When applied on pre-cancerous or cancerous skin cells, Efudex topical prevents them from being able to grow.
How do I take Efudex?
Efudex is dosed as follows:
Actinic keratoses
- Fluorouracil 2% and 5%: Apply a thin layer to cover the skin spots or growths on the affected area(s) twice daily. The typical length of treatment is 2 to 4 weeks. But it can take 1 to 2 months after the end of treatment to notice complete healing of the skin
Basal cell carcinoma
- Fluorouracil 5% only: Apply a thin layer to cover the skin spots or growths on the affected area(s) twice daily. The typical length of treatment is 3 to 6 weeks, but can be extended to up to 3 months, if needed
Is it safe for me to take Efudex?
Efudex is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. You should not use this medication if you are pregnant.
Efudex Common Side Effects
Common side effects of Efudex:
- Crusting of the skin
- Stinging or burning feeling of the skin
- Itchiness
- Soreness on the skin
- Scarring
Efudex Serious Side Effects
Serious side effects are rare with Efudex. Contact your healthcare provider immediately if you experience any of the following.
- Rare toxicity reaction: Stomach pains, bloody diarrhea, vomiting, fever, chills, skin rash, painful sores in the mouth
Effects of other drugs, drug classes and over-the-counter products on Efudex
There are no major drug interactions listed for Efudex. However, always let your physician and pharmacist know about any other medications or supplements (including prescribed and over-the-counter medications, vitamins, and dietary or herbal supplements) that you are currently taking.
Who makes Efudex?
Bausch Health
Is Efudex safe in pregnancy?
Efudex is contraindicated in women who are or may become pregnant during therapy. If this drug is used during pregnancy, or if the patient becomes pregnant while using this drug, the patient should be apprised of the potential hazard to the fetus
What is the generic name for Efudex?
Medical Disclaimer
NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.
The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.
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