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MEDICAL INFORMATION
Drospirenone and Estradiol Key Facts
What dosages is Drospirenone And Estradiol available in?
Drospirenone And Estradiol is available as an oral tablet that contains 0.25 mg drospirenone/0.5 mg estradiol or 0.5 mg drospirenone/1 mg estradiol.
What is Drospirenone And Estradiol used for?
Drospirenone And Estradiol is a type of hormone replacement therapy that is used to treat:
- Moderate-to-severe vasomotor symptoms (VMS) of menopause, like hot flashes and night sweats
- Moderate-to-severe symptoms of vulvar and vaginal atrophy, like vaginal dryness and irritation
How does Drospirenone And Estradiol work?
Drospirenone And Estradiol replaces estrogen and progesterone hormones during menopause:
- Estradiol replaces the estrogen that your body loses during menopause, which lessens the symptoms of vaginal dryness and hot flashes.
- Drospirenone is a progestin. It acts like progesterone and helps balance the effect of estrogen on the growth of your uterine lining.
How do I take Drospirenone And Estradiol?
Drospirenone And Estradiol is typically taken by mouth once daily.
Is it safe for me to take Drospirenone And Estradiol?
Drospirenone And Estradiol is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. You should not use this medication in the following:
- Abnormal vaginal bleeding that your gynecologist doesn’t know about or you haven’t gone to them about
- Currently have or have had breast cancer
- Estrogen-dependent cancers (e.g., endometrial cancer, ovarian cancer)
- High risk for developing a blood clot
- History of blood clots, stroke, or heart attack
- Have a bleeding disorder
- Kidney problems
- Liver problems
- Currently have Addison’s disease or a disease of your adrenal glands
- Have had your uterus (womb) removed
Drospirenone And Estradiol Common Side Effects
Common side effects of Drospirenone And Estradiol:
- Breast pain or discomfort
- Vaginal bleeding
- Belly pain
- Headache
- Nausea
Drospirenone And Estradiol Serious Side Effects
Serious side effects are rare with Drospirenone And Estradiol. Contact your healthcare provider immediately if you experience any of the following:
- Heart attack: chest pain, belly discomfort, sweating, nausea, dizziness
- Stroke: sudden numbness or weakness in the arm, leg, or face, confusion, trouble seeing, headache, difficulty walking
- Deep vein thrombosis (blood clot in the leg): leg cramp, swelling, pain, muscle tightness
- Pulmonary embolism (blood clot in the lung): cough, chest pain, trouble breathing, racing heart
- Liver or gallbladder problems: yellowing of the skin or the whites of the eyes, tiredness, pain in the right upper stomach, dark urine
- Unusual vaginal bleeding, vaginal discharge, or pelvic pain
Effects of other drugs, drug classes and over-the-counter products on Drospirenone And Estradiol
The following medications may interact with Drospirenone And Estradiol:
- Inducers and inhibitors of CYP3A4 may affect estrogen drug metabolism and
- Decrease or increase the estrogen plasma concentration.
- Medications that increase your potassium levels.
Who makes Drospirenone And Estradiol?
Various FDA-approved generic manufacturers
Is Drospirenone And Estradiol safe in pregnancy?
Drospirenone And Estradiol should not be used during pregnancy. Talk to your doctor if you are already pregnant or if you have plans on becoming pregnant.
What is the brand name for Drospirenone And Estradiol?
Medical Disclaimer
NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.
The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.
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