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MEDICAL INFORMATION
Diroximel Fumarate Key Facts
What dosages is Diroximel Fumarate available in?
Diroximel Fumarate is available as a 231 mg delayed-release capsule.
What is Diroximel Fumarate used for?
Diroximel Fumarate is indicated for the treatment of relapsing forms of multiple sclerosis (MS), to include clinically isolated syndrome, relapsing-remitting disease, and active secondary progressive disease, in adults.
How does Diroximel Fumarate work?
Diroximel Fumarate is a type of disease-modifying therapy (DMT) called a fumaric acid derivative. More specifically, Diroximel Fumarate is a Nrf2 activator. It’s not exactly known how Diroximel Fumarate helps with multiple sclerosis. But the medication is thought to turn on Nrf2 pathways in the body to help protect against damage to nerve cells and lessen inflammation.
How do I take Diroximel Fumarate?
Diroximel Fumarate is dosed as follows:
- Starting dose: 231 mg twice a day, by mouth, for 7 days
- Maintenance dose after 7 days: 462 mg (administered as two 231 mg
- Capsules) by mouth twice a day
Is it safe for me to take Diroximel Fumarate?
Diroximel Fumarate is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. You should not use this medication in the following:
- Known hypersensitivity to Diroximel Fumarate, dimethyl fumarate, or to any of the excipients in the product
- Co-administration with dimethyl fumarate
Diroximel Fumarate Common Side Effects
Common side effects of Diroximel Fumarate:
- Flushing
- Stomach pain
- Diarrhea
- Nausea
Diroximel Fumarate Serious Side Effects
Serious side effects are rare with Diroximel Fumarate. Contact your healthcare provider immediately if you experience any of the following:Severe allergic reaction: hives, rash, red skin, swelling of the lips or tongue, closing of the throat, difficulty breathing
Severe infection: fever, difficulty breathing, diarrhea, weakness, vision problems, thinking or memory problems, personality changes
Serious liver problems: pain on the right side of your stomach, yellowing of your skin or the whites of your eyes (jaundice), loss of appetite, dark urine
Serious Stomach or gut issues: severe stomach pain; severe vomiting, constipation, or diarrhea; rectal bleeding; bloody diarrhea
Effects of other drugs, drug classes and over-the-counter products on Diroximel Fumarate
The following medications may interact with Diroximel Fumarate:
- Dimethyl fumarate
Who makes Diroximel Fumarate?
Various FDA-approved generic manufacturers
Is Diroximel Fumarate safe in pregnancy?
Based on animal data, Diroximel Fumarate may cause fetal harm. Talk to your doctor if you are already pregnant or if you have plans on becoming pregnant. They will recommend what is best for you.
What is the brand name for Diroximel Fumarate?
Medical Disclaimer
NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.
The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.
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