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DIANE-35

DIANE-35

Used for Acne

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Manufactured by Bayer Healthcare

*You can pay as little as $0 per fill using Drug Coupons or Patient Assistance Programs. Subject to applicability & eligibility requirements.

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DIANE-35 cost saving options available to you

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    Buy your DIANE-35 without insurance from Canada at discounts of up to 90% using NowPatient's Canadian Prescription savings program.
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    Drug Coupons

    Obtain your DIANE-35 for as little as $0 per fill. Suitable for insured individuals only.
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    Patient Assistance Programs

    Obtain your DIANE-35 at no cost. Suitable for insured, underinsured and uninsured individuals
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DIANE-35 Uses, Side Effects, Interactions, Warnings & Dosing

What is DIANE-35?

What is DIANE-35?

DIANE-35 is the brand name for ethinylestradiol/cyproterone acetate oral tablets.

What dosages is DIANE-35 available in?

What dosages is DIANE-35 available in?

DIANE-35 is available as an oral tablet that contains ethinylestradiol 0.035 mg and cyproterone acetate 2 mg. It also comes with 7 placebo tablets.

What is DIANE-35 used for?

What is DIANE-35 used for?

DIANE-35 is an antiandrogen and an estrogen that is used for:
Moderate to severe acne related to androgen-sensitivity (with or without seborrhoea) and/or hirsutism in women of reproductive age. The prevention of pregnancy.

How does DIANE-35 work?

How does DIANE-35 work?

DIANE-35 is an antiandrogen and estrogen combination. These medicines work by blocking the effects of a class of hormones called androgens. Cyproterone also supresses ovulation and therefore has a contraceptive effect.

How do I take DIANE-35?

How do I take DIANE-35?

DIANE-35 comes as a pre-packaged course (28 days) of medication. There are 21 active tablets and 7 placebo tablets and they don’t contain any active medication. The typical dose is to take 1 active tablet by mouth daily for 21 days, followed by 1 placebo tablet daily for the remaining 7 days. The tablets must be taken in order as shown on the medication packaging.

Is it safe for me to take DIANE-35?

Is it safe for me to take DIANE-35?

DIANE-35 is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. You should not use this medication in the following.

  • Hypersensitivity to the active substances or to any of the excipients.
  • Venous thrombosis present or in history (deep venous thrombosis, pulmonary embolism).
  • Arterial thrombosis present or in history (e.g. myocardial infarction) or prodromal conditions (e.g.
    angina pectoris and transient ischaemic attack).
  • Presence or history of cerebrovascular accident
  • History of migraine with focal neurological symptoms
  • The presence of a severe or multiple risk factor(s) for venous or arterial thrombosis such as, diabetes mellitus with vascular symptoms, severe hypertension, or severe dyslipoproteinaemia
  • Hereditary or acquired predisposition for venous or arterial thrombosis, such as activated protein C (APC) resistance, antithrombin-III-deficiency, protein C deficiency, protein S deficiency, hyperhomocysteinaemia and antiphospholipid-antibodies (anticardiolipin-antibodies, lupus anticoagulant)
  • Severe hepatic disease as long as liver function values have not returned to normal
  • Use of direct-acting antiviral (DAA) medicinal products containing ombitasvir, paritaprevir, or dasabuvir, and combinations of these.
  • Presence or history of liver tumours (benign or malignant)
  • Known or suspected sex-steroid influenced malignancies (e.g. of the genital organs or the breasts)
    Undiagnosed vaginal bleeding
  • Concomitant use with another hormonal contraceptive.
    Known or suspected pregnancy
  • Lactation
DIANE-35 Common Side Effects

DIANE-35 Common Side Effects

Common side effects of DIANE-35:

  • Nausea
  • Abdominal pain
  • Increased weight
  • Headache
  • Depression or mood changes
  • Brest pain
  • Breast tenderness
DIANE-35 Serious Side Effects

DIANE-35 Serious Side Effects

Serious side effects are rare with DIANE-35. Contact your healthcare provider immediately if you experience any of the following.

  • Heart attack: chest pain, stomach discomfort, sweating, nausea, dizziness
  • Stroke: sudden numbness or weakness in the arm, leg, or face, confusion, trouble seeing, headache, difficulty walking
  • Deep vein thrombosis (blood clot in the leg): leg cramp, swelling, pain, muscle tightness
  • Pulmonary embolism (blood clot in the lung): cough, chest pain, trouble breathing, racing heart
  • Liver problems: yellowing of the skin or the whites of the eyes, tiredness, stomach pain
Effects of other drugs, drug classes and over-the-counter products on DIANE-35

Effects of other drugs, drug classes and over-the-counter products on DIANE-35

The following medications may interact with DIANE-35:

  • Substances increasing the clearance of DIANE-35 (diminished efficacy by enzyme-induction), e.g.: Phenytoin, barbiturates, primidone, carbamazepine, rifampicin, and possibly also oxcarbazepine topiramate, felbamate, griseofulvin, and products containing St. John’s wort
  • Substances with variable effects on the clearance of DIANE-35, e.g.: When co-administered with combined oral contraceptives, many HIV/HCV protease inhibitors and nonnucleoside reverse transcriptase inhibitors can increase or decrease plasma concentrations of estrogen or progestin. These changes may be clinically relevant in some cases
  • Substances decreasing the clearance of DIANE-35 (enzyme inhibitors)
  • Strong and moderate CYP3A4 inhibitors such as azole antifungals (e.g. itraconazole, voriconazole fluconazole), verapamil, macrolides (e.g. clarithromycin, erythromycin), diltiazem and grapefruit juice can increase plasma concentrations of the estrogen or the progestin or both
Who makes DIANE-35?

Who makes DIANE-35?

Bayer Healthcare

Is DIANE-35 safe in pregnancy?

Is DIANE-35 safe in pregnancy?

DIANE-35 should not be used during pregnancy. Inform your doctor immediately if you become pregnant while taking DIANE-35.

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What to do if you missed your DIANE-35 dose

The FDA's medical product safety reporting program for health professionals, patients and consumers.

Learn more about reporting side effects
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NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.

The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.

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