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dextromethorphan/quinidine Uses, Side Effects, Interactions, Warnings & Dosing

What dosages is dextromethorphan/quinidine available in?

What dosages is dextromethorphan/quinidine available in?

dextromethorphan/quinidine is available as a tablet with 20 mg of dextromethorphan hydrobromide and 10 mg of quinidine sulfate.

What is dextromethorphan/quinidine used for?

What is dextromethorphan/quinidine used for?

dextromethorphan/quinidine is a combination medication that is used to treat pseudobulbar affect (PBA). PBA occurs secondary to a variety of otherwise unrelated neurologic conditions, and is characterized by involuntary, sudden, and frequent episodes of laughing and/or crying.

How does dextromethorphan/quinidine work?

How does dextromethorphan/quinidine work?

dextromethorphan/quinidine has 2 medications. Dextromethorphan bromide balances out certain chemicals in the brain that affect mood and behavior while quinidine helps prevent dextromethorphan from being broken down too quickly in the body.

How do I take dextromethorphan/quinidine?

How do I take dextromethorphan/quinidine?

dextromethorphan/quinidine is typically taken once daily for 1 week and then increased to 1 tablet every 12 hours.

Is it safe for me to take dextromethorphan/quinidine?

Is it safe for me to take dextromethorphan/quinidine?

dextromethorphan/quinidine is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you.

dextromethorphan/quinidine Common Side Effects

dextromethorphan/quinidine Common Side Effects

Common side effects of dextromethorphan/quinidine include:

  • Diarrhea
  • Dizziness
  • Cough
  • Vomiting
  • Weakness, lack of energy
  • Swelling in your hands and feet
dextromethorphan/quinidine Serious Side Effects

dextromethorphan/quinidine Serious Side Effects

Serious side effects are rare with dextromethorphan/quinidine however they can include:

  • Low platelets
  • Serotonin syndrome
  • Liver damage
  • Abnormal heart rhythm
Effects of other drugs, drug classes and over-the-counter products on dextromethorphan/quinidine

Effects of other drugs, drug classes and over-the-counter products on dextromethorphan/quinidine

The following medications may interact with dextromethorphan/quinidine:

  • desipramine
  • paroxetine
  • digoxin
Who makes dextromethorphan/quinidine?

Who makes dextromethorphan/quinidine?

Various FDA-approved generic manufacturers

Is dextromethorphan/quinidine safe in pregnancy?

Is dextromethorphan/quinidine safe in pregnancy?

dextromethorphan/quinidine hasn’t been well-studied in pregnancy or during breastfeeding. But animal studies suggest it can harm babies if taken by mothers during pregnancy. If you’re pregnant, thinking of becoming pregnant, or are breastfeeding, talk to your provider about your options for PBA.


What to do if you missed your dextromethorphan/quinidine dose

The FDA's medical product safety reporting program for health professionals, patients and consumers.

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Medical Disclaimer

NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.

The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.

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