DESYREL
Used for Depression and Anxiety
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Manufactured by Pragma Pharmaceuticals
*You can pay as little as $0 per fill using Drug Coupons or Patient Assistance Programs. Subject to applicability & eligibility requirements.
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DESYREL Uses, Side Effects, Interactions, Warnings & Dosing
What is DESYREL?
DESYREL is the brand name for trazodone and is available as an oral tablet.
What dosages is DESYREL available in?
DESYREL is available as a 50 mg, 100 mg, 150 mg, and 300 mg oral tablet.
What is DESYREL used for?
DESYREL is an atypical antidepressant and is used to treat major depressive disorder (MDD).
How does DESYREL work?
DESYREL is an atypical antidepressant. More specifically, it’s considered a serotonin antagonist and reuptake inhibitor (SARI). The exact way it works to improve your mood isn’t well-understood. But it’s thought to affect the levels of serotonin in the brain, which are chemicals involved in regulating your mood.
How do I take DESYREL?
DESYREL is typically taken by mouth with starting dose of 150 mg divided into smaller doses and taken throughout the day to treat depression. Your physician might raise your dose slowly over time to a maximum dose of 400 mg daily.
Is it safe for me to take DESYREL?
DESYREL is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. You should not use this medication if you have taken an MAOI within the past 14 days.
DESYREL Common Side Effects
Common side effects of DESYREL include:
- Sleepiness
- Dry mouth
- Dizziness or lightheadedness
- Headache
- Blurred vision
- Nausea or vomiting
DESYREL Serious Side Effects
Serious side effects are rare with DESYREL. Contact your healthcare provider immediately if you experience any of the following.
- Suicidal thoughts or behaviors
- Serotonin syndrome: fast heart rate, dizziness, sweating, flushing, tremor (shakiness), muscle stiffness, muscle twitching or spasms, uncoordinated movement, distress, seizures, distress, hallucinations, coma
- Abnormal heart rhythm (QT prolongation): chest pounding, short of breath, chest pain, feeling faint or lightheaded
- Severe bleeding: bruising that doesn’t improve, black-colored stools, pink or red-colored urine, coughing up or vomiting blood, or unusual bleeding from the nose or gums
- Low blood sodium levels: nausea, fatigue, headache, confusion, disoriented, hallucinations (seeing things that aren’t real), seizures, unconsciousness
Effects of other drugs, drug classes and over-the-counter products on DESYREL
The following medications may interact with DESYREL:
- CNS Depressants – DESYREL may enhance effects of alcohol, barbiturates, or other CNS depressants
- CYP3A4 Inhibitors – Consider DESYREL dose reduction based on tolerability
- CYP3A4 Inducers – Increase in DESYREL dosage may be necessary
- Digoxin or Phenytoin – Monitor for increased digoxin or phenytoin serum levels
- Warfarin – Monitor for increased or decreased prothrombin time
Who makes DESYREL?
Pragma Pharmaceuticals
Is DESYREL safe in pregnancy?
DESYREL may cause fetal harm based on animal studies. You should talk to your healthcare provider before taking this medication if you are pregnant.
The FDA's medical product safety reporting program for health professionals, patients and consumers.
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Medical Disclaimer
NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.
The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.
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