Key facts about Dalfampridine
What dosages is Dalfampridine available in?
Dalfampridine is available as a 10 mg extended-release tablet.
What is Dalfampridine used for?
Dalfampridine is a potassium channel blocker that is used to improve walking in adults with multiple sclerosis (MS).
How does Dalfampridine work?
Dalfampridine is a potassium channel blocker. In multiple sclerosis (MS), damaged nerves don’t work well because too much potassium leaves the nerve cells through proteins called potassium channels. It’s not exactly known how Dalfampridine works to improve walking in people with multiple sclerosis (MS). But it’s thought that it helps damaged nerves work again by blocking potassium channels on these nerve cells.
How do I take Dalfampridine?
Dalfampridine is typically taken twice daily (approximately 12 hours apart). It can be taken with or without food.
Is it safe for me to take Dalfampridine?
Dalfampridine is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. You should not take this medication if you have a history of seizure, moderate or severe kidney impairment (CrCl≤50 mL/min), or a history of hypersensitivity to Dalfampridine or 4-aminopyridine.
Dalfampridine Common Side Effects
Common side effects of Dalfampridine include:
- Urinary tract infection
- Insomnia
- Dizziness
- Headache
- Nausea
- Weakness or lack of energy
Dalfampridine Serious Side Effects
Serious side effects are rare with Dalfampridine. Serious Side Effects
Contact your healthcare provider immediately if you experience any of the following.
- Severe allergic reactions: hives, rash, red skin, swelling of the lips or tongue, closing of the throat, difficulty breathing
- Seizures
Effects of other drugs, drug classes and over-the-counter products on Dalfampridine
The following medications may interact with Dalfampridine:
- OCT2 Inhibitors – Concomitant use may cause an increased exposure and potential risk of seizures
Who makes Dalfampridine?
Various FDA-approved generic manufacturers
Is Dalfampridine safe in pregnancy?
Dalfampridine may cause harm to your unborn baby, based on animal studies. Talk with your healthcare provider about the risks of taking Dalfampridine if you become pregnant.
