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dalfampridine

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Is the cost of your dalfampridine too expensive?

You may qualify for programs where you can pay as little as $0 per fill, subject to income and insurance status.

This content is intended for US audiences only

NowPatient offers cost effective access to dalfampridine for everyone including those who are uninsured, those who have commercial insurance as well as those who are enrolled into state or federal programs like Medicaid, Medicare Part D, full Low Income Subsidy (LIS, “Extra Help”), TRICARE or Veterans (VA) Benefits.

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Table of contents
OverviewWhat can I do if I am commercially insured but cannot afford my dalfampridine?What can I do if I am uninsured and cannot afford my dalfampridine?What can I do if I am insured with Medicare and cannot afford my dalfampridine?Am I eligible for the Rx Advantage Card and how much does dalfampridine cost without insurance?What will my out-of-pocket cost be for dalfampridine when using the Rx Advantage Card?Is it legal for me to pay cash for dalfampridine even though I have insurance?Does the Rx Advantage Card work with Medicare or any other federal or state insurance plans?Does the Rx Advantage Card work with Commercial Insurance?How do I check prices for dalfampridine and how do I use the Rx Advantage Card?Do I need to pay for the Rx Advantage Card?Is there a dalfampridine co-pay program?Is there a dalfampridine Patient Assistance Program (PAP)?What should I do if I take too much dalfampridine?What are the benefits of NowPatient?What is generic dalfampridine?FDA approval of dalfampridineActive ingredient of dalfampridineUS brand name of dalfampridine and manufacturerUK brand name of dalfampridine and manufacturerPrescription requirement for dalfampridineAvailability of dalfampridine in the UK with NHS prescriptionConditions treated by dalfampridineHow does dalfampridine work?Forms of dalfampridine availableDosage of dalfampridineDirections for dalfampridine useWarnings and precautions for dalfampridineDrug interactions for dalfampridineUse of dalfampridine during pregnancyUse of dalfampridine while breastfeedingPossible side effects of dalfampridineSimilar drugs to dalfampridineSourcesPeople also asked
Navin Khosla NowPatientGreen tick
Medically reviewed by Navin Khosla, BPharm and written by Rajive Patel, BPharm - Updated on 25 Jan 2024
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What can I do if I am commercially insured but cannot afford my dalfampridine?

If you are commercially insured and you cannot afford your copay or co-insurance you can opt for purchasing dalfampridine outside of your plan using the Rx Advantage card, with costs that are usually lower than a typical plan copay. If you elect to use this method, out of pocket costs do not contribute towards your plan deductibles.

If you cannot afford the cash price possibly due to income constraints, then there is the option of applying to state assistance programs like Medicaid. Often, you may be able to receive your dalfampridine without any costs at all. You can check Medicaid eligibility in your state by following this link HealthCare.gov. The government site is easy to use and you can select your state and it will navigate you to the appropriate contact point to make the application.

What can I do if I am uninsured and cannot afford my dalfampridine?

If you cannot afford the cash price of dalfampridine using the Rx Advantage card then there is the option of applying to state programs like Medicaid. Often, you may be able to receive your dalfampridine without any costs at all. You can check Medicaid eligibility in your state by following this link HealthCare.gov. The government site is easy to use and you can select your state and it will navigate you to the appropriate contact point to make the application.

What can I do if I am insured with Medicare and cannot afford my dalfampridine?

If you are insured with Medicare and have Part D or an Advantage drug plan but cannot afford your copay or co-insurance element (for example if you are in the coverage gap or Donut Hole) then you have a number of options:

Option

Savings Information

RX ADVANTAGE CARD

You can use the Rx Advantage to purchase the medication outside of your plan at prices that may be lower than you copay or co-insurance element. If you elect to use this method, out of pocket costs do not contribute towards your plan deductibles.

LOW INCOME SUBSIDY

If this is still too expensive or unaffordable then you can apply for federal support like Low Income Subsidy (LIS). To be eligible for Low Income Subsidy, you need to be resident in one of the 50 States or the District of Columbia. You can check eligibility online at SSA Medicare D Extra Help. You can also call Social Security at 1-800-772-1213 (TTY 1-800-325-0778).

MEDICAID

Alternatively, you can check Medicaid eligibility in your state by following this link to the HealthCare.gov. The government site is easy to use and you can select your state and it will navigate you to the appropriate contact point to make the application. State Medicaid programs may cover the full cost of your medication.

Am I eligible for the Rx Advantage Card and how much does dalfampridine cost without insurance?

Our website gives savings options to customers who wish to purchase dalfampridine, as either a brand or generic, without the constraints of insurance. By using the Rx Advantage Card, users can save up to 90% on the cost of their medication. The card can be used at over 65,000 pharmacies nationwide, across America. Even if you are insured, in most cases the cash price will be significantly cheaper than your existing co-pay. NowPatient is able to negotiate discounts on bulk drug purchases with pharmacy owners meaning you can access lower medication prices at nearby pharmacies using our card that can be conveniently stored in your NowPatient account.

What will my out-of-pocket cost be for dalfampridine when using the Rx Advantage Card?

Your out-of-pocket (OOP) cost will effectively be the discounted cash price you pay for dalfampridine using the Rx Advantage Card. If you are insured, your OOP expense can not be used against your plan deductible, if your plan has a deductible.

Yes. The Rx Advantage card is especially useful for people who have High-deductible health plans (HDHPs). It can be used for insured, uninsured, and underinsured persons.

Does the Rx Advantage Card work with Medicare or any other federal or state insurance plans?

No. We do not bill any federal or state insurance including Medicare Part D (standalone drug coverage) or Medicare Advantage (combined health and drug benefit). When you purchase your medication using the NowPatient Rx Advantage Card, you will be doing so out of pocket. The spend will not count towards your plan deductibles or gaps in the event you have a plan with a deductible. The out-of-pocket dalfampridine cash price you pay can be typically cheaper than your plan copay.

Does the Rx Advantage Card work with Commercial Insurance?

We do not bill your commercial insurance. When you purchase your medication using the Rx Advantage Card, from NowPatient, you will be doing so out of your pocket. The spend will not count towards your plan deductibles or gaps in the event you have a plan with a deductible. The out-of-pocket dalfampridine cash price you pay can be typically cheaper than your plan copay.

How do I check prices for dalfampridine and how do I use the Rx Advantage Card?

You can search for the prices at nearby pharmacies using our website. Simply search your medication and enter your ZIP Code and we will show you the price of your drug at nearby pharmacies. If you are happy with the quote, you need to create an account with NowPatient and generate your card. Next, simply go to the pharmacy and fill your dalfampridine Rx. Ask the pharmacy to run the card and check the price, even if they tell you they have another card they use. Your card is stored safely in your NowPatient account.

Do I need to pay for the Rx Advantage Card?

No. The Rx Advantage prescription savings card is FREE to use and store for NowPatient users.

Is there a dalfampridine co-pay program?

Generic medications like dalfampridine do not have co-pay card savings options. A Copay program, if available, would normally be for the brand name version of dalfampridine. You can search the brand name of dalfampridine and check to see if a co-pay program exists. Co-pay cards are programs run by pharmaceutical companies that offer you a direct way to lower your out-of-pocket costs for prescription drugs for eligible patients. The copay cards essentially allow physicians to prescribe medications that are clinically preferred.

Is there a dalfampridine Patient Assistance Program (PAP)?

Generic medications like dalfampridine do not have PAP savings options. A Patient assistance program, if available would normally be for the brand name version of dalfampridine. You can search the brand name of dalfampridine and check to see if a co-PAP exists. PAPs are programs that are run and sponsored by pharmaceutical companies. They offer uninsured, insured, or underinsured individuals access to high-cost brand-name medications, which may otherwise be unaffordable.

What should I do if I take too much dalfampridine?

Call your doctor right away or seek immediate medical attention if your symptoms do not improve or they become worse after using dalfampridine. You can also call 800-222-1222 to reach the American Association of Poison Control Centers or use its online resource if you think you've used too much dalfampridine. But if you have severe symptoms, call 911 (or your local emergency number) immediately or go to the nearest emergency room.

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What is generic dalfampridine?

Generic dalfampridine refers to the non-brand-name version of the medication. It contains the same active ingredient as the brand-name drug but is typically less expensive.

FDA approval of dalfampridine

Dalfampridine is approved by the U.S. Food and Drug Administration (FDA) for the improvement of walking in adults with multiple sclerosis (MS).

Active ingredient of dalfampridine

The active ingredient of dalfampridine is dalfampridine.

US brand name of dalfampridine and manufacturer

Dalfampridine is available under the brand name Ampyra in the US. The medication is manufactured by Acorda Therapeutics, Inc.

UK brand name of dalfampridine and manufacturer

In the UK, dalfampridine is available under the brand name Fampyra. The manufacturer may vary depending on the brand name.

Prescription requirement for dalfampridine

A prescription (Rx) is required for dalfampridine in both the US and the UK.

Availability of dalfampridine in the UK with NHS prescription

Dalfampridine is available in the UK with an NHS prescription.

Conditions treated by dalfampridine

Dalfampridine is a medication used to treat a specific symptom experienced by people with multiple sclerosis (MS). It helps increase walking speed and may enhance overall mobility.

MS is a chronic neurological condition that affects the central nervous system, causing various symptoms such as muscle weakness, difficulty with coordination, and problems with mobility. One common symptom of MS is impaired walking ability, which can significantly impact a person’s daily life and independence.

How does dalfampridine work?

Dalfampridine is in a class of medications called potassium channel blockers. Dalfampridine is an extended-release form of 4-aminopyridine (4-AP), a broad-spectrum lipophilic potassium channel blocker. The mechanism of action of dalfampridine is related to its ability to increase nerve conduction in demyelinated axons.
In MS, the immune system mistakenly attacks the protective myelin sheath that covers nerve fibers in the central nervous system. This results in impaired nerve function and can lead to various symptoms, including difficulties with walking and coordination. Dalfampridine works by blocking specific potassium channels on the surface of nerve fibers, which helps to improve the conduction of electrical signals along the damaged nerves.
By blocking these channels, dalfampridine prolongs the duration of the action potential, allowing nerves to transmit signals more effectively. This can enhance the overall function of demyelinated nerves and improve walking speed and mobility in individuals with MS.
It is important to note that dalfampridine does not treat the underlying cause of MS or slow down disease progression. Instead, it focuses on improving specific symptoms related to walking ability. Additionally, dalfampridine may not be suitable for everyone, and it is essential to consult with a healthcare professional before starting this medication.
Overall, the mechanism of action of dalfampridine involves blocking potassium channels to enhance nerve conduction in demyelinated axons, leading to improved walking ability in individuals with MS.

Forms of dalfampridine available

Dalfampridine is available in the form of oral tablets.

Dosage of dalfampridine

The dosage of dalfampridine may vary depending on individual patient factors and response to treatment. It is important to follow the prescribed dosage instructions provided by the healthcare provider.
The recommended dose of dalfampridine is 10 mg twice daily. This medication is commonly prescribed for individuals with multiple sclerosis (MS) to help improve their walking ability. It is important to follow the prescribed dosage given by your healthcare provider and not exceed the recommended dose. Taking more than the recommended dose can increase the risk of side effects and may not provide any additional benefits. If you have any questions or concerns about your dosage of dalfampridine, it is best to consult with your doctor or pharmacist for further guidance.

Directions for dalfampridine use

Dalfampridine should be taken exactly as directed by the healthcare provider. The tablets should be swallowed whole and should not be crushed, chewed, or split. The medication is usually taken twice daily, with approximately 12 hours between doses.
Dalfampridine is available in the form of extended-release tablets and is usually taken orally twice daily. The dosage may vary depending on individual factors, and it is important to follow the prescribed dosage and instructions provided by the healthcare provider.

Warnings and precautions for dalfampridine

  • Dalfampridine should not be used in individuals with a history of seizures or moderate to severe renal impairment
  • Dalfampridine should be used with caution in patients with a history of seizures or kidney problems, as it may exacerbate these conditions. Additionally, it should not be used in individuals with a history of hypersensitivity or allergic reactions to 4-aminopyridine
  • It may interact with certain medications, including other drugs that affect kidney function and certain medications that prolong the QT interval. It is important to inform the healthcare provider about all medications being taken
  • It is important to inform your healthcare professional about all medications you are taking, including prescription, over-the-counter meds, and supplements. They can help determine any potential adverse reactions or contraindications and make necessary adjustments to your treatment plan to ensure your safety

Drug interactions for dalfampridine

Medications that are known to interact with dalfampridine include:

  • Combining dalfampridine with other MS medications, such as disease-modifying therapies, should be done with caution and under the guidance of a healthcare professional
  • Drugs that lower the seizure threshold, such as antipsychotics, antidepressants, and certain antibiotics, may increase the risk of seizures when combined with dalfampridine
  • Dalfampridine is primarily eliminated from the body through the kidneys. Medications that affect kidney function, such as diuretics or certain antibiotics, may alter the clearance of dalfampridine and increase the drug’s blood levels
  • Dalfampridine is metabolized in the liver. Medications that affect liver function, such as certain antifungal medications or antiretroviral drugs, may interfere with the metabolism of dalfampridine and increase its blood levels
  • Dalfampridine can potentially prolong the QT interval, which can increase the risk of serious heart rhythm abnormalities. Combining dalfampridine with medications that also have this effect, such as certain antibiotics or antipsychotics, may further increase the risk

It is important to note that this is not an exhaustive list of medications that may interact with dalfampridine. Always consult with your healthcare provider before starting or stopping any medications while taking dalfampridine.

Use of dalfampridine during pregnancy

The use of dalfampridine during pregnancy has not been well-studied. Consultation with a healthcare provider is necessary to discuss the potential risks and benefits.

Use of dalfampridine while breastfeeding

It is unknown whether dalfampridine passes into breast milk. Consultation with a healthcare provider is necessary to evaluate the potential risks and benefits in individual cases.

Possible side effects of dalfampridine

Common side effects of dalfampridine may include:

  • Urinary tract infections
  • Dizziness
  • Insomnia
  • Headache
  • Constipation
  • Nausea

It is important to be aware of the potential serious side effects that may occur:

  • One of the most significant risks associated with dalfampridine is the increased likelihood of seizures. Therefore, it is crucial for individuals with a history of seizures or those at a higher risk of experiencing seizures to inform their healthcare provider before starting dalfampridine
  • Some individuals may develop an allergic reaction to dalfampridine. Symptoms of an allergic reaction can include hives, difficulty breathing, and swelling of the face, lips, tongue, or throat. It is important to seek immediate medical attention if any signs of an allergic reaction are observed
  • Dalfampridine is primarily eliminated from the body through the kidneys. In rare cases, it can cause kidney problems, such as decreased kidney function or kidney failure. Monitoring kidney function through regular testing is essential while taking dalfampridine

Similar drugs to dalfampridine

There are no other medications with the same active ingredient as dalfampridine specifically for improving walking in MS. However, other treatment options for managing MS symptoms include disease-modifying therapies and symptomatic relief medications.

Sources

Medical Disclaimer

NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information in this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.

The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.

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