DalfampridinePrices, Coupons & Savings

Mail Order Pharmacy

1. Medication
   You save
   

   US ONLY
2. Dalfampridine ER

   Generic for Ampyra

   Rx

   10mg

   30 extended release tablets $11.4 USD

   30 extended release tablets $11.4 USD - 0.38 USD/extended release tablet
   Save $1383.00

   Get started
   Get started

Do you need a prescription for dalfampridine?

Yes, dalfampridine is only available with a valid physician Rx.

How much is dalfampridine without Insurance in the US?

Our website gives two competitive savings options to US customers who wish to purchase dalfampridine, as either a brand or generic, if available. The first is access to medications through our mail-order online pharmacy. The second is by using the Now Patient Rx Advantage Card, which can be used in over 65,000 pharmacies nationwide, across America. If you are insured, then in most cases, the cash price will be significantly cheaper than the copay.

What will my out-of-pocket cost be for dalfampridine in the US?

There are no out-of-pocket (OOP) costs because we are currently only offering a cash-based option to purchase medications.

Is Now Patient a dalfampridine savings card?

Yes. Save up to 90% on your dalfampridine with the FREE Now Patient Rx Advantage card*.
*Based on the difference between the U&C submitted by the pharmacy and the price the patients pay.

Can you handle Rx transfers for home delivery in the US?

Yes. If you use the mail-order online pharmacy option, then we can handle requests by you to have your prescription transferred to our pharmacy for home delivery. We can even help you manage your refills by giving you timely reminders, so you do not run out of your medication.

Is Now Patient a dalfampridine coupon provider in the US?

No. Now Patient does not provide dalfampridine coupons or FREE dalfampridine samples.

Do you accept commercial, Medicare or Medicaid coverage for dalfampridine in the US?

No. Currently, we only offer cash-based options for purchase, therefore we do not require your insurance benefit details. In the future, our plan is to be able to handle commercial insurance, Medicare and Medicaid including cases where you have multiple health plans that provide benefit coverage (e.g. Medicaid and Commercial). We also anticipate being able to handle more complex scenarios such as using primary insurance combined with a manufacturer copay assistance program.

Does Now Patient work with Medicare?

Our cash-based prices for medications are typically cheaper than Medicare copays. We do not bill Medicare Part D (standalone drug coverage) or Medicare Advantage (combined health and drug coverage). When you purchase your medication from Now Patient, you will be doing so out of your pocket. The spend will not count towards your plan deductibles or gaps.

Does Now Patient work with Commercial Insurance?

Our cash-based prices for medications are typically cheaper than commercial plan copays. We do not bill your commercial plan. When you purchase your medication from Now Patient, you will be doing so out of your pocket. The spend will not count towards your plan deductibles or gaps.

What should you do if you use too much dalfampridine?

US

Call your doctor right away or seek immediate medical attention if your symptoms do not improve or they become worse after using dalfampridine. You can also call 800-222-1222 to reach the American Association of Poison Control Centers or use its online resource if you think you’ve used too much dalfampridine. But if you have severe symptoms, call 911 (or your local emergency number) immediately or go to the nearest emergency room.

UK

If you think it is an emergency, call 999 or find your nearest A&E
If you need help now, but it’s not an emergency go to 111.nhs.uk or call 111. Alternatively you can speak to one of our pharmacists or use the Now Patient app to make an appointment with your GP.

What should I do if I miss my dose?

There are occasions when people forget to take their medication at correct prescribed times. This may not only have an effect on potentially making the medication less effective but it may also inadvertently lead to taking doses too close together, thereby increasing the risks of side effects.

Click here to find out what to do if you forgot to take your medication

What is generic dalfampridine?

Generic dalfampridine refers to the non-brand-name version of the medication. It contains the same active ingredient as the brand-name drug but is typically less expensive.

FDA approval of dalfampridine

Dalfampridine is approved by the U.S. Food and Drug Administration (FDA) for the improvement of walking in adults with multiple sclerosis (MS).

Active ingredient of dalfampridine

The active ingredient of dalfampridine is dalfampridine.

US brand name of dalfampridine and manufacturer

Dalfampridine is available under the brand name Ampyra in the US. The medication is manufactured by Acorda Therapeutics, Inc.

UK brand name of dalfampridine and manufacturer

In the UK, dalfampridine is available under the brand name Fampyra. The manufacturer may vary depending on the brand name.

Prescription requirement for dalfampridine

A prescription (Rx) is required for dalfampridine in both the US and the UK.

Availability of dalfampridine in the UK with NHS prescription

Dalfampridine is available in the UK with an NHS prescription.

Conditions treated by dalfampridine

Dalfampridine is a medication used to treat a specific symptom experienced by people with multiple sclerosis (MS). It helps increase walking speed and may enhance overall mobility.

MS is a chronic neurological condition that affects the central nervous system, causing various symptoms such as muscle weakness, difficulty with coordination, and problems with mobility. One common symptom of MS is impaired walking ability, which can significantly impact a person’s daily life and independence.

How does dalfampridine work?

Dalfampridine is in a class of medications called potassium channel blockers. Dalfampridine is an extended-release form of 4-aminopyridine (4-AP), a broad-spectrum lipophilic potassium channel blocker. The mechanism of action of dalfampridine is related to its ability to increase nerve conduction in demyelinated axons.
In MS, the immune system mistakenly attacks the protective myelin sheath that covers nerve fibers in the central nervous system. This results in impaired nerve function and can lead to various symptoms, including difficulties with walking and coordination. Dalfampridine works by blocking specific potassium channels on the surface of nerve fibers, which helps to improve the conduction of electrical signals along the damaged nerves.
By blocking these channels, dalfampridine prolongs the duration of the action potential, allowing nerves to transmit signals more effectively. This can enhance the overall function of demyelinated nerves and improve walking speed and mobility in individuals with MS.
It is important to note that dalfampridine does not treat the underlying cause of MS or slow down disease progression. Instead, it focuses on improving specific symptoms related to walking ability. Additionally, dalfampridine may not be suitable for everyone, and it is essential to consult with a healthcare professional before starting this medication.
Overall, the mechanism of action of dalfampridine involves blocking potassium channels to enhance nerve conduction in demyelinated axons, leading to improved walking ability in individuals with MS.

Forms of dalfampridine available

Dalfampridine is available in the form of oral tablets.

Dosage of dalfampridine

The dosage of dalfampridine may vary depending on individual patient factors and response to treatment. It is important to follow the prescribed dosage instructions provided by the healthcare provider.
The recommended dose of dalfampridine is 10 mg twice daily. This medication is commonly prescribed for individuals with multiple sclerosis (MS) to help improve their walking ability. It is important to follow the prescribed dosage given by your healthcare provider and not exceed the recommended dose. Taking more than the recommended dose can increase the risk of side effects and may not provide any additional benefits. If you have any questions or concerns about your dosage of dalfampridine, it is best to consult with your doctor or pharmacist for further guidance.

Directions for dalfampridine use

Dalfampridine should be taken exactly as directed by the healthcare provider. The tablets should be swallowed whole and should not be crushed, chewed, or split. The medication is usually taken twice daily, with approximately 12 hours between doses.
Dalfampridine is available in the form of extended-release tablets and is usually taken orally twice daily. The dosage may vary depending on individual factors, and it is important to follow the prescribed dosage and instructions provided by the healthcare provider.

Warnings and precautions for dalfampridine

• Dalfampridine should not be used in individuals with a history of seizures or moderate to severe renal impairment
• Dalfampridine should be used with caution in patients with a history of seizures or kidney problems, as it may exacerbate these conditions. Additionally, it should not be used in individuals with a history of hypersensitivity or allergic reactions to 4-aminopyridine
• It may interact with certain medications, including other drugs that affect kidney function and certain medications that prolong the QT interval. It is important to inform the healthcare provider about all medications being taken
• It is important to inform your healthcare professional about all medications you are taking, including prescription, over-the-counter meds, and supplements. They can help determine any potential adverse reactions or contraindications and make necessary adjustments to your treatment plan to ensure your safety

Drug interactions for dalfampridine

Medications that are known to interact with dalfampridine include:

• Combining dalfampridine with other MS medications, such as disease-modifying therapies, should be done with caution and under the guidance of a healthcare professional
• Drugs that lower the seizure threshold, such as antipsychotics, antidepressants, and certain antibiotics, may increase the risk of seizures when combined with dalfampridine
• Dalfampridine is primarily eliminated from the body through the kidneys. Medications that affect kidney function, such as diuretics or certain antibiotics, may alter the clearance of dalfampridine and increase the drug’s blood levels
• Dalfampridine is metabolized in the liver. Medications that affect liver function, such as certain antifungal medications or antiretroviral drugs, may interfere with the metabolism of dalfampridine and increase its blood levels
• Dalfampridine can potentially prolong the QT interval, which can increase the risk of serious heart rhythm abnormalities. Combining dalfampridine with medications that also have this effect, such as certain antibiotics or antipsychotics, may further increase the risk

It is important to note that this is not an exhaustive list of medications that may interact with dalfampridine. Always consult with your healthcare provider before starting or stopping any medications while taking dalfampridine.

Use of dalfampridine during pregnancy

The use of dalfampridine during pregnancy has not been well-studied. Consultation with a healthcare provider is necessary to discuss the potential risks and benefits.

Use of dalfampridine while breastfeeding

It is unknown whether dalfampridine passes into breast milk. Consultation with a healthcare provider is necessary to evaluate the potential risks and benefits in individual cases.

Possible side effects of dalfampridine

Common side effects of dalfampridine may include:

• Urinary tract infections
• Dizziness
• Insomnia
• Headache
• Constipation
• Nausea

It is important to be aware of the potential serious side effects that may occur:

• One of the most significant risks associated with dalfampridine is the increased likelihood of seizures. Therefore, it is crucial for individuals with a history of seizures or those at a higher risk of experiencing seizures to inform their healthcare provider before starting dalfampridine
• Some individuals may develop an allergic reaction to dalfampridine. Symptoms of an allergic reaction can include hives, difficulty breathing, and swelling of the face, lips, tongue, or throat. It is important to seek immediate medical attention if any signs of an allergic reaction are observed
• Dalfampridine is primarily eliminated from the body through the kidneys. In rare cases, it can cause kidney problems, such as decreased kidney function or kidney failure. Monitoring kidney function through regular testing is essential while taking dalfampridine

Similar drugs to dalfampridine

There are no other medications with the same active ingredient as dalfampridine specifically for improving walking in MS. However, other treatment options for managing MS symptoms include disease-modifying therapies and symptomatic relief medications.

Sources

• FDA Prescribing Information for Dalfampridine
• MHRA product information for Dalfampridine
• NHS UK