Cyproheptadine Generic

FDA badge
Looking for ways to save up to 90%* on your FDA-approved branded and generic medications?
You could enjoy savings using Now Patient’s mail-order online pharmacy or the Now Patient Rx Advantage Card at over 65,000 pharmacies.
US Flag
United States
*Based on the difference between the U&C price submitted and the price the patient paid, as of April 2023.

Mail Order Pharmacy

  1. Medication
    You save
    US Flag
  2. Cyproheptadine HCl
    Generic for Periactin
    30 tablets $5.1 USD
    Save $24.00
  3. Cyproheptadine HCl
    Generic for Periactin
    473mL (160) syrups $15.25 USD
    Save $139.95
Now Patient Parcel

Or register now to use our savings card

Savings Card

Save up to 90% of your branded or generic medications using the Now Patient Rx Advantage Card

Do you need a prescription for cyproheptadine?

Yes, cyproheptadine is only available with a valid physician Rx.

How much is cyproheptadine without Insurance in the US?

Our website gives two competitive savings options to US customers who wish to purchase cyproheptadine, as either a brand or generic, if available. The first is access to medications through our mail-order online pharmacy. The second is by using the Now Patient Rx Advantage Card, which can be used in over 65,000 pharmacies nationwide, across America. If you are insured, then in most cases, the cash price will be significantly cheaper than the copay.

What will my out-of-pocket cost be for cyproheptadine in the US?

There are no out-of-pocket (OOP) costs because we are currently only offering a cash-based option to purchase medications.

Is Now Patient a cyproheptadine savings card?

Yes. Save up to 90% on your cyproheptadine with the FREE Now Patient Rx Advantage card*.
*Based on the difference between the U&C submitted by the pharmacy and the price the patients pay.

Can you handle Rx transfers for home delivery in the US?

Yes. If you use the mail-order online pharmacy option, then we can handle requests by you to have your prescription transferred to our pharmacy for home delivery. We can even help you manage your refills by giving you timely reminders, so you do not run out of your medication.

Is Now Patient a cyproheptadine coupon provider in the US?

No. Now Patient does not provide cyproheptadine coupons or FREE cyproheptadine samples.

Do you accept commercial, Medicare or Medicaid coverage for cyproheptadine in the US?

No. Currently, we only offer cash-based options for purchase, therefore we do not require your insurance benefit details. In the future, our plan is to be able to handle commercial insurance, Medicare and Medicaid including cases where you have multiple health plans that provide benefit coverage (e.g. Medicaid and Commercial). We also anticipate being able to handle more complex scenarios such as using primary insurance combined with a manufacturer copay assistance program.

Does Now Patient work with Medicare?

Our cash-based prices for medications are typically cheaper than Medicare copays. We do not bill Medicare Part D (standalone drug coverage) or Medicare Advantage (combined health and drug coverage). When you purchase your medication from Now Patient, you will be doing so out of your pocket. The spend will not count towards your plan deductibles or gaps.

Does Now Patient work with Commercial Insurance?

Our cash-based prices for medications are typically cheaper than commercial plan copays. We do not bill your commercial plan. When you purchase your medication from Now Patient, you will be doing so out of your pocket. The spend will not count towards your plan deductibles or gaps.

What should you do if you use too much cyproheptadine?


Call your doctor right away or seek immediate medical attention if your symptoms do not improve or they become worse after using cyproheptadine. You can also call 800-222-1222 to reach the American Association of Poison Control Centers or use its online resource if you think you’ve used too much cyproheptadine. But if you have severe symptoms, call 911 (or your local emergency number) immediately or go to the nearest emergency room.


If you think it is an emergency, call 999 or find your nearest A&E
If you need help now, but it’s not an emergency go to 111.nhs.uk or call 111. Alternatively you can speak to one of our pharmacists or use the Now Patient app to make an appointment with your GP.

What should I do if I miss my dose?

There are occasions when people forget to take their medication at correct prescribed times. This may not only have an effect on potentially making the medication less effective but it may also inadvertently lead to taking doses too close together, thereby increasing the risks of side effects.

Click here to find out what to do if you forgot to take your medication

What is generic cyproheptadine?

US brand name of cyproheptadine and manufacturer

Cyproheptadine is available in the US under various brand names, including Periactin and cyproheptadine HCl. It is manufactured by multiple pharmaceutical companies.

UK brand name of cyproheptadine and manufacturer

Cyproheptadine is available in the UK under the brand name Periactin. It is manufactured by Merck Sharp & Dohme Limited.

Is cyproheptadine available in the UK on the NHS?

Yes, cyproheptadine is available on the NHS in the UK. It can be prescribed by healthcare professionals for eligible patients.

Prescription requirement for cyproheptadine

Cyproheptadine is a prescription medication and requires a prescription from a healthcare provider.

FDA approval of cyproheptadine

Cyproheptadine has received FDA approval for the treatment of various conditions, including allergic reactions, allergic rhinitis, and appetite stimulation in underweight patients.

Active ingredient of cyproheptadine and mechanism of action

Cyproheptadine contains the active ingredient cyproheptadine hydrochloride. It is an antihistamine with anticholinergic properties. It works by blocking the effects of histamine, a natural substance that the body releases during allergic reactions. By blocking histamine, cyproheptadine helps reduce symptoms such as itching, sneezing, and runny nose.

Uses of cyproheptadine

Cyproheptadine is a serotonin and histamine antagonist primarily used for the treatment of allergic reactions and allergic conditions, including allergic rhinitis (hay fever), hives, and itching. It may also be prescribed off-label for other conditions, such as appetite stimulation in underweight patients.

Forms of cyproheptadine

Cyproheptadine is available in various forms, including oral tablets and oral syrup. The specific form and strength will depend on the intended use and the formulation of the medication.

Dosage of cyproheptadine

The dosage of cyproheptadine will vary depending on the specific condition being treated, individual patient characteristics, and response to therapy. It is important to follow the dosage instructions provided by your healthcare provider.

Contraindications and warnings for cyproheptadine

  • Cyproheptadine may cause drowsiness and impair your ability to perform tasks that require alertness. Avoid driving or operating machinery until you know how cyproheptadine affects you
  • It may interact with other medications, so it is important to inform your healthcare provider about all the medications you are taking, including prescription drugs, over-the-counter medications, and herbal supplements
  • Tell your doctor if you have asthma, glaucoma, heart disease (irregular heartbeat), high blood pressure, kidney disease, stomach problems, an overactive thyroid, or problems urinating due to an enlarged prostate
  • It is not known if this drug passes into breast milk. Speak to your doctor before breast-feeding

Side effects of cyproheptadine

Cyproheptadine may cause adverse effects in some individuals. Common side effects may include:

  • Drowsiness
  • Dry mouth
  • Dizziness
  • Blurred vision
  • Constipation
  • Weight gain
  • Hypotension

Get medical help right away if you have serious side effects such as a life-threatening allergic reaction. Symptoms include hives, trouble breathing, shortness of breath, swelling of your face, tongue or throat, skin rash, and severe skin reactions. Promptly report any adverse events to a healthcare professional for medical advice.

Interactions with other drugs

Cyproheptadine may interact with other medications, including sedatives, tranquilizers, and monoamine oxidase inhibitors (MAOIs). It is important to inform your healthcare provider about all the prescription drugs, non-prescription over the counter medication, supplements, and vitamins you are taking to avoid potential drug interactions.



Now Patient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information in this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.

The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.

Stefano Mirabello Medical Reviewer
Pharmacist / B.Pharm
To improve the lives of everyone by making high-quality care accessible and convenient

As technologists and clinicians, we built Now Patient to be more than just an online pharmacy.  We are here to improve lives.  Our service gives you access to smart features & resources that can help empower you to take control of your health and improve your health outcomes.  All this, in one place, for FREE.  We strive to bring a fresh perspective to managing health. Not play by the rules. Now Patient can be accessed by downloading the App or using your web browser.

A mobile app displaying a health care service.
Join the thousands of happy customers in the US and UK already using Now Patient

Manage your health and prescriptions all in one place for FREE.  Available to use by downloading the App, or using your web browser.

Reminders page
Your Questions Answered
For your peace of mind, we can answer your health questions quickly
If you want to learn more about the range of services that we provide which can help manage and improve your health, then just click the button below.
Find your answers