COLUMVI
Used for Cancer
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Manufactured by Genentech, Inc.
*You can pay as little as $0 per fill using Drug Coupons or Patient Assistance Programs. Subject to applicability & eligibility requirements.
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COLUMVI Uses, Side Effects, Interactions, Warnings & Dosing
What is COLUMVI?
COLUMVI is the brand name for glofitamab-gxbm IV infusion.
What dosages is COLUMVI available in?
COLUMVI is available as a 2.5 mg/2.5 mL (1 mg/mL) or 10 mg/10 mL (1 mg/mL) single-dose vial.
What is COLUMVI used for?
COLUMVI is a monoclonal antibody used to treat lymphoma.
How does COLUMVI work?
COLUMVI works by helping your immune system slow or stop the spread of cancer cells.
How do I take COLUMVI?
COLUMVI is an IV infusion given by your care team in a hospital or clinic setting.
Your first cycle is given as follows:
Day 1 Obinutuzumab 1,000 mg
Day 8 Step-up dose 1 2.5 mg
Day 15 Step-up dose 2 10 mg
Cycle 2-12: Day 1 30 mg
Is it safe for me to take COLUMVI?
COLUMVI is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you.
COLUMVI Common Side Effects
- Common side effects of COLUMVI:
- Bone pain
- Constipation
- Diarrhea
- Fatigue
- Muscle pain
- Skin rash
COLUMVI Serious Side Effects
Serious side effects are rare with COLUMVI. Side effects that you should report to your care team as soon as possible:
Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat
Fever, chills, unusual weakness or fatigue, loss of appetite, nausea, headache, dizziness, feeling faint or lightheaded, shortness of breath, fast or irregular heartbeat, which may be signs of cytokine release syndrome
Infection—fever, chills, cough, sore throat, wounds that don’t heal, pain or trouble when passing urine, general feeling of discomfort or being unwell
Low red blood cell level—unusual weakness or fatigue, dizziness, headache, trouble breathing
Pain, tingling, or numbness in the hands or feet, muscle weakness, change in vision, confusion or trouble speaking, loss of balance or coordination, trouble walking, seizures
Swelling and pain of the tumor site or lymph nodes
Unusual bruising or bleeding
Effects of other drugs, drug classes and over-the-counter products on COLUMVI
- The following medications may interact with COLUMVI:
- For certain CYP substrates where minimal concentration changes may lead to serious adverse reactions
- monitor for toxicities or drug concentrations of such CYP substrates when coadministered with COLUMVI.
Who makes COLUMVI?
Genentech, Inc.
Is COLUMVI safe in pregnancy?
COLUMVI may harm your unborn baby.
Females who are able to become pregnant:
Your healthcare provider should do a pregnancy test before you start treatment with COLUMVI.
You should use effective birth control (contraception) during treatment and for 1 month after your last dose of COLUMVI. Talk to your healthcare provider about what birth control method is right for you during this time.
Tell your healthcare provider right away if you become pregnant or think you may be pregnant during treatment with COLUMVI.
The FDA's medical product safety reporting program for health professionals, patients and consumers.
Learn more about reporting side effects
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Medical Disclaimer
NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.
The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.
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